Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 1920..2398 Replicon plasmid unnamed2
Accession NZ_CP046443
Organism Pseudomonas coronafaciens pv. coronafaciens strain B19001

Toxin (Protein)


Gene name relE Uniprot ID H1ZX33
Locus tag GMO17_RS27210 Protein ID WP_003348565.1
Coordinates 2105..2398 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2S4HLF9
Locus tag GMO17_RS27205 Protein ID WP_003348562.1
Coordinates 1920..2105 (+) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GMO17_RS27195 1..1314 + 1314 WP_024651588.1 replication initiation protein -
GMO17_RS27200 1540..1833 + 294 WP_024651587.1 HU family DNA-binding protein -
GMO17_RS27205 1920..2105 + 186 WP_003348562.1 hypothetical protein Antitoxin
GMO17_RS27210 2105..2398 + 294 WP_003348565.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GMO17_RS27215 2538..3065 + 528 WP_003348567.1 hypothetical protein -
GMO17_RS27220 3062..3736 - 675 WP_080269136.1 MobA/MobL family protein -
GMO17_RS27225 4219..6249 - 2031 WP_024651585.1 methyl-accepting chemotaxis protein -
GMO17_RS27230 6933..7385 + 453 WP_122346733.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..45971 45971


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11136.84 Da        Isoelectric Point: 6.2150

>T144263 WP_003348565.1 NZ_CP046443:2105-2398 [Pseudomonas coronafaciens pv. coronafaciens]
MLPIFWLESADNDLAAIIEYIGSRDIAAAERLWQRLRGIVLPLSEHPYLYAISDRVPGMREIVAHPNYLVFYRVTSTRIE
VVNVVHARQEYPQTGLA

Download         Length: 294 bp

>T144263 NZ_CP061801:c2163142-2162831 [Enterobacter mori]
ATGCACGTAGTCTCAAGAGCGCCTTTCGACGCGGCCACCAGACAATTTCCTAATCAAGCACTCGCCCTGCACGATCTTTA
CCGGGTGCTAAAGAAGGAACACTACCCGTCACCGGACGATATGAGAAAGCGATTCCCCAGCCTGGACAGGATGAAATACA
GGGAAAAATGGTGGGTCATTGATGTGGGTGGCGGGCATTTAAGAGTGATGTTTTTTACTGATTTTGAGAGAGGAAAGATT
TTCATCAAACACATCAGCACCCACGCAGAGTATGACAAGCTCACGGACCTCTACCGGAGAACGAAAGAATGA

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7134.04 Da        Isoelectric Point: 6.4675

>AT144263 WP_003348562.1 NZ_CP046443:1920-2105 [Pseudomonas coronafaciens pv. coronafaciens]
MIDRSPIVSEFETEELEANYTAWLRAKVEASLADSRPAIPHDEVERRMAERLARLRHRRAS

Download         Length: 186 bp

>AT144263 NZ_CP061801:c2162834-2162415 [Enterobacter mori]
ATGAATTATGCAGCAGTCATCAAAGCGGCAAACGATCTGACCAACGCGCTCCCTTTCCTGGGCTCAAGCCCGTCGCGACA
AGATTATGAGGATGCGCTAGCGCTGGTGGAGTATCTGGTCGAACACGAACCCGATAGCCCGCTGGTGGAGATGCTCACCG
CCAAAATCGATCAATACGAAAACGAGTCCCCGGAGTTTGCAGATTTTAACGCGCGTGTTGCCAGCATTCCGTCAGGCGTT
GCGTTATTGCGAACGCTGATGGACCAGTACCAACTCACTCAGAGCGACTTCGAGACAGAGATTGGTAAAAAGTCTCTGGT
GAGCCGGATCCTTAACGGACAGCGTACGCTAACGCTGGATCATATGCGTGCACTGGCGAAGCGTTTTGGCGTGCCGGTGA
GTGCGTTTGTGGGGAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A193SFZ9

Antitoxin

Source ID Structure
AlphaFold DB A0A2S4HLF9

References