Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2073297..2073568 Replicon chromosome
Accession NZ_CP046416
Organism Escherichia coli strain LZYWN_4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2073427..2073530 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2073297..2073568 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJV83_RS10105 2069852..2070514 - 663 WP_000944256.1 exodeoxyribonuclease X -
GJV83_RS10110 2070538..2071194 - 657 WP_182116893.1 carbon-nitrogen hydrolase family protein -
GJV83_RS10115 2071296..2071526 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GJV83_RS10120 2071665..2072039 + 375 WP_094322552.1 CopC domain-containing protein YobA -
GJV83_RS10125 2072043..2072915 + 873 WP_094322553.1 copper homeostasis membrane protein CopD -
GJV83_RS10130 2072928..2073269 + 342 WP_000976472.1 YebY family protein -
- 2073297..2073568 - 272 - - Antitoxin
- 2073427..2073530 + 104 - - Toxin
GJV83_RS10135 2073665..2074321 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
GJV83_RS10140 2074322..2074513 - 192 WP_001338167.1 YebW family protein -
GJV83_RS10145 2074618..2074854 - 237 WP_206970355.1 DUF1480 family protein -
GJV83_RS10150 2074972..2076411 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T144234 NZ_CP046416:2073427-2073530 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT144234 NZ_CP046416:c2073568-2073297 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References