Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
| Location | 140595..141142 | Replicon | chromosome |
| Accession | NZ_CP046411 | ||
| Organism | Vibrio parahaemolyticus strain 19-021-D1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | GNY17_RS01220 | Protein ID | WP_025793438.1 |
| Coordinates | 140840..141142 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U3A269 |
| Locus tag | GNY17_RS01215 | Protein ID | WP_005448240.1 |
| Coordinates | 140595..140852 (+) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GNY17_RS01160 | 135824..135916 | + | 93 | WP_072612521.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01165 | 136386..136478 | + | 93 | WP_005494820.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01170 | 136506..136886 | + | 381 | WP_104411071.1 | hypothetical protein | - |
| GNY17_RS01175 | 137003..137350 | + | 348 | WP_025793492.1 | DNA-binding protein | - |
| GNY17_RS01180 | 137376..137468 | + | 93 | WP_072606053.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01185 | 137494..137868 | + | 375 | WP_025793490.1 | hypothetical protein | - |
| GNY17_RS01190 | 138502..138591 | + | 90 | WP_074190212.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01195 | 138640..139245 | + | 606 | WP_140142847.1 | hypothetical protein | - |
| GNY17_RS01200 | 139271..139363 | + | 93 | WP_080259420.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01205 | 139806..139934 | + | 129 | WP_080277532.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01210 | 139962..140435 | + | 474 | WP_025534629.1 | hypothetical protein | - |
| GNY17_RS01215 | 140595..140852 | + | 258 | WP_005448240.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| GNY17_RS01220 | 140840..141142 | + | 303 | WP_025793438.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| GNY17_RS01225 | 141309..141854 | + | 546 | WP_025793483.1 | hypothetical protein | - |
| GNY17_RS01230 | 142009..142548 | + | 540 | WP_025793484.1 | hypothetical protein | - |
| GNY17_RS01235 | 142563..142655 | + | 93 | WP_005494856.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01240 | 142700..142984 | + | 285 | WP_017448465.1 | nucleotide pyrophosphohydrolase | - |
| GNY17_RS01245 | 142992..143102 | + | 111 | WP_082798391.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01250 | 143134..143439 | + | 306 | WP_021453216.1 | hypothetical protein | - |
| GNY17_RS01255 | 143583..143930 | + | 348 | WP_005448158.1 | nucleic acid-binding protein | - |
| GNY17_RS01260 | 143956..144048 | + | 93 | WP_078235736.1 | DUF3265 domain-containing protein | - |
| GNY17_RS27790 | 144453..144596 | + | 144 | WP_168937153.1 | DUF3265 domain-containing protein | - |
| GNY17_RS01275 | 144689..145066 | + | 378 | WP_156216529.1 | hypothetical protein | - |
| GNY17_RS01280 | 145208..145933 | + | 726 | WP_025793457.1 | class I SAM-dependent methyltransferase | - |
| GNY17_RS01285 | 145955..146047 | + | 93 | WP_079882702.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | - | 34290..156591 | 122301 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11536.51 Da Isoelectric Point: 5.8623
>T144221 WP_025793438.1 NZ_CP046411:140840-141142 [Vibrio parahaemolyticus]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQAIFSKVERLVAFPESGRIPPELAHLSYREVVVNPCRIFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQAIFSKVERLVAFPESGRIPPELAHLSYREVVVNPCRIFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
Download Length: 303 bp
>T144221 NZ_CP061779:1594109-1594390 [Pseudomonas aeruginosa]
ATGACCTATAAGCTCGAGTTCCTGCCCTCAGCGCTGAAGGAATGGGAGAAGCTGGGTCATACGGTGCGTGAGCAGGCAAA
GAAAAAACTGCGTGAGCGGCTGGAAGCACCAAAGGTACAGGCTGATGCCCTCAGGGATCTGCCTGGCCACTACAAGATCA
AGCTCCGAACAGCAGGCTATCGATTGGTCTATAATGTCGAGGATGATCGGGTGGTTGTGATTGTGGTCGCAGTGGGCAAG
CGTGAACGAAGTGCAGCTTACAAGGCAGCAGGTAAGCGTTAG
ATGACCTATAAGCTCGAGTTCCTGCCCTCAGCGCTGAAGGAATGGGAGAAGCTGGGTCATACGGTGCGTGAGCAGGCAAA
GAAAAAACTGCGTGAGCGGCTGGAAGCACCAAAGGTACAGGCTGATGCCCTCAGGGATCTGCCTGGCCACTACAAGATCA
AGCTCCGAACAGCAGGCTATCGATTGGTCTATAATGTCGAGGATGATCGGGTGGTTGTGATTGTGGTCGCAGTGGGCAAG
CGTGAACGAAGTGCAGCTTACAAGGCAGCAGGTAAGCGTTAG
Antitoxin
Download Length: 86 a.a. Molecular weight: 9606.10 Da Isoelectric Point: 6.7269
>AT144221 WP_005448240.1 NZ_CP046411:140595-140852 [Vibrio parahaemolyticus]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK
Download Length: 258 bp
>AT144221 NZ_CP061779:1593874-1594119 [Pseudomonas aeruginosa]
ATGCAGAGTGTTTTGGCTGACGTTGCCGTGAGCGTTTCTGAGCTGAAGAAAAACCCCACCGGTGTCATGGCTGGTGCGGG
TGGCATGCCGGTCGCAGTTCTCAATCATAACCGCGTGATGGGGTACATGGTGCCAGCCGAGCTGTACGAGCAGATGTTGG
ACCGTTTGGACGATCTGGATCTGATCGATGTCGTTAACGCGCGCTCCGGTGAGAAGGGTGTGCCGGTGAACCTGGATGAC
CTATAA
ATGCAGAGTGTTTTGGCTGACGTTGCCGTGAGCGTTTCTGAGCTGAAGAAAAACCCCACCGGTGTCATGGCTGGTGCGGG
TGGCATGCCGGTCGCAGTTCTCAATCATAACCGCGTGATGGGGTACATGGTGCCAGCCGAGCTGTACGAGCAGATGTTGG
ACCGTTTGGACGATCTGGATCTGATCGATGTCGTTAACGCGCGCTCCGGTGAGAAGGGTGTGCCGGTGAACCTGGATGAC
CTATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|