144219

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 91059..91618 Replicon chromosome
Accession NZ_CP046411
Organism Vibrio parahaemolyticus strain 19-021-D1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GNY17_RS00735 Protein ID WP_025793434.1
Coordinates 91059..91337 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GNY17_RS00740 Protein ID WP_025793433.1
Coordinates 91334..91618 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GNY17_RS00690 86152..86250 + 99 Protein_126 antibiotic biosynthesis monooxygenase -
GNY17_RS00695 86305..87225 - 921 WP_010446562.1 IS5 family transposase -
GNY17_RS00705 87731..88108 + 378 WP_086583718.1 hypothetical protein -
GNY17_RS00710 88224..88709 + 486 WP_148299771.1 hypothetical protein -
GNY17_RS00715 88846..89346 + 501 WP_025506945.1 hypothetical protein -
GNY17_RS00725 90037..90915 + 879 WP_025793435.1 hypothetical protein -
GNY17_RS00730 90938..91030 + 93 WP_079390553.1 DUF3265 domain-containing protein -
GNY17_RS00735 91059..91337 - 279 WP_025793434.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
GNY17_RS00740 91334..91618 - 285 WP_025793433.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GNY17_RS00745 91898..92422 + 525 WP_025793432.1 hypothetical protein -
GNY17_RS27775 92781..92873 + 93 WP_193230369.1 DUF3265 domain-containing protein -
GNY17_RS00755 92902..93303 + 402 WP_025793431.1 DUF2007 domain-containing protein -
GNY17_RS00760 93456..93851 + 396 WP_025793430.1 hypothetical protein -
GNY17_RS00765 93987..94366 + 380 Protein_139 energy transducer TonB -
GNY17_RS00770 94394..94483 + 90 WP_077281740.1 DUF3265 domain-containing protein -
GNY17_RS00775 94511..94987 + 477 WP_025793429.1 GNAT family N-acetyltransferase -
GNY17_RS00780 94996..95106 + 111 WP_079757379.1 DUF3265 domain-containing protein -
GNY17_RS00785 95136..95669 + 534 WP_025793428.1 cysteine hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 86305..87225 920
- inside Integron - - 34290..156591 122301


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-70)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10893.59 Da        Isoelectric Point: 4.4442

>T144219 WP_025793434.1 NZ_CP046411:c91337-91059 [Vibrio parahaemolyticus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIDVKVENLLEQPLMGVQRDGIRGRLLIIPEISMIISHWVEGDIIRVM
RVLHQKQKFPTD

Download         Length: 279 bp

>T144219 NZ_CP061779:913021-913608 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAGTTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
AGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11039.37 Da        Isoelectric Point: 9.2167

>AT144219 WP_025793433.1 NZ_CP046411:c91618-91334 [Vibrio parahaemolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKALSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT144219 NZ_CP061779:913675-914529 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCCGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCACGTGCACAGCAGCTTCGCCCTGGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTGGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAGATGGAGCAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGCGTGCCGCGCTTCGCCGACAGCGTGATCCACGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGACCCGCTGGCGTGAGACGGTGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCCCGTGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCGCTGGAGGAACTGGCGGCGGCGGTCAATCTGTCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGGCAGCGCCGCCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGCTGGAGGTGGCCCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGGCCTACGGCGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCATCCTTGACGATCTACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References