Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2182992..2183263 Replicon chromosome
Accession NZ_CP046396
Organism Escherichia coli strain ampC_0069

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2183122..2183225 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2182992..2183263 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GNX12_RS10210 2179547..2180209 - 663 WP_000944256.1 exodeoxyribonuclease X -
GNX12_RS10215 2180233..2180889 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
GNX12_RS10220 2180991..2181221 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GNX12_RS10225 2181360..2181734 + 375 WP_022645803.1 CopC domain-containing protein YobA -
GNX12_RS10230 2181738..2182610 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
GNX12_RS10235 2182623..2182964 + 342 WP_000976472.1 YebY family protein -
- 2182992..2183263 - 272 - - Antitoxin
- 2183122..2183225 + 104 - - Toxin
GNX12_RS10240 2183360..2184016 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
GNX12_RS10245 2184017..2184208 - 192 WP_001296140.1 YebW family protein -
GNX12_RS10250 2184313..2184549 - 237 WP_001295499.1 DUF1480 family protein -
GNX12_RS10255 2184667..2186106 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T144158 NZ_CP046396:2183122-2183225 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT144158 NZ_CP046396:c2183263-2182992 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References