Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2773406..2774030 Replicon chromosome
Accession NZ_CP046392
Organism Acinetobacter indicus strain WMB-7

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GK020_RS13400 Protein ID WP_087662214.1
Coordinates 2773406..2773798 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GK020_RS13405 Protein ID WP_171065118.1
Coordinates 2773785..2774030 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GK020_RS13385 2768734..2771010 - 2277 WP_156189531.1 TRAP transporter large permease subunit -
GK020_RS13390 2771191..2771763 - 573 WP_156189532.1 rhombosortase -
GK020_RS13395 2771819..2772892 - 1074 WP_087662213.1 hypothetical protein -
GK020_RS13400 2773406..2773798 - 393 WP_087662214.1 hypothetical protein Toxin
GK020_RS13405 2773785..2774030 - 246 WP_171065118.1 succinate dehydrogenase assembly factor 2 Antitoxin
GK020_RS13410 2774226..2775398 + 1173 WP_005180239.1 acyl-CoA dehydrogenase family protein -
GK020_RS13415 2775486..2776976 - 1491 WP_156189533.1 NAD(P)/FAD-dependent oxidoreductase -
GK020_RS13420 2777175..2777540 - 366 WP_004754212.1 50S ribosomal protein L17 -
GK020_RS13425 2777560..2778567 - 1008 WP_087662217.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14932.76 Da        Isoelectric Point: 10.4540

>T144149 WP_087662214.1 NZ_CP046392:c2773798-2773406 [Acinetobacter indicus]
MSMAKRDFQLKPSRLALLFQLSLLILFSVLSFQLLHPLLWLLGLLLAAVSYYGFQRRSQLTALAHLDGAEWSLQFNSGPK
IQRGLLDHILDHQLYLVLYFHHAPVKSAVIWRDQVPLAEWKALKTLAKTI

Download         Length: 393 bp

>T144149 NZ_CP061754:1936128-1936382 [Escherichia coli O18ac:H14]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9758.15 Da        Isoelectric Point: 4.9108

>AT144149 WP_171065118.1 NZ_CP046392:c2774030-2773785 [Acinetobacter indicus]
ISLEERKVIYRARRGLKEIDVYFDPYVKNYYLTADPEEKATFAALVEQEDPDLLDWFMEVSEPPRPEMRELIRKLKHYVH
G

Download         Length: 246 bp

>AT144149 NZ_CP061754:1935880-1936131 [Escherichia coli O18ac:H14]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References