Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1922228..1922373 Replicon chromosome
Accession NZ_CP046381
Organism Klebsiella pneumoniae strain BD_DM_782

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1922264..1922366 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1922228..1922373 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GM011_RS09260 1917358..1919418 + 2061 WP_004151449.1 oligopeptidase B -
GM011_RS09265 1919422..1920081 - 660 WP_020324964.1 exodeoxyribonuclease X -
GM011_RS09270 1920160..1920390 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GM011_RS09275 1920503..1920877 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GM011_RS09280 1920881..1921750 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
GM011_RS09285 1921767..1922105 + 339 WP_002911404.1 YebY family protein -
- 1922228..1922373 - 146 - - Antitoxin
- 1922264..1922366 + 103 - - Toxin
GM011_RS09290 1922742..1922885 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GM011_RS09295 1922990..1923958 - 969 WP_004151446.1 VirK/YbjX family protein -
GM011_RS09300 1924115..1924768 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
GM011_RS09305 1924765..1924956 - 192 WP_002911395.1 YebW family protein -
GM011_RS09310 1925054..1925293 - 240 WP_002911393.1 YebV family protein -
GM011_RS09315 1925409..1926842 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T144132 NZ_CP046381:1922264-1922366 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT144132 NZ_CP046381:c1922373-1922228 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References