Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 3102544..3103343 Replicon chromosome
Accession NZ_CP046377
Organism Pectobacterium polaris strain PZ1

Toxin (Protein)


Gene name hepT Uniprot ID A0A6P1S6Q8
Locus tag GMX10_RS14135 Protein ID WP_039482641.1
Coordinates 3102544..3102963 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID A0A6P1S5H0
Locus tag GMX10_RS14140 Protein ID WP_039482638.1
Coordinates 3102960..3103343 (-) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GMX10_RS14120 3098209..3098790 + 582 WP_039482649.1 dCTP deaminase -
GMX10_RS14125 3098854..3100689 + 1836 WP_039482646.1 outer membrane assembly protein AsmA -
GMX10_RS14130 3101148..3102500 + 1353 WP_161546882.1 anaerobic C4-dicarboxylate transporter DcuC -
GMX10_RS14135 3102544..3102963 - 420 WP_039482641.1 DUF86 domain-containing protein Toxin
GMX10_RS14140 3102960..3103343 - 384 WP_039482638.1 nucleotidyltransferase domain-containing protein Antitoxin
GMX10_RS14145 3103483..3105069 - 1587 WP_039482635.1 TerC family protein -
GMX10_RS14150 3105803..3106900 + 1098 WP_161546883.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
GMX10_RS14155 3107018..3108154 + 1137 WP_161546884.1 polysaccharide export protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(12-129)

Antitoxin

Polymerase beta, nucleotidyltransferase

(4-93)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16138.51 Da        Isoelectric Point: 7.3845

>T144120 WP_039482641.1 NZ_CP046377:c3102963-3102544 [Pectobacterium polaris]
MTDILLNKSSTIQRCLRRIREEFDTKEEFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKHLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFERFIKEVARYSDSQHL

Download         Length: 420 bp

>T144120 NZ_CP061749:1938440-1938691 [Escherichia coli O15:H12]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14312.49 Da        Isoelectric Point: 5.2241

>AT144120 WP_039482638.1 NZ_CP046377:c3103343-3102960 [Pectobacterium polaris]
MFDKIVSTLKKQIPDIKIIYLFGSQATGNARADSDVDIAILATRALDPVERWELSNQLAKEVGRDVDLIDLLQASTVLKM
EIVRNGKLLYDAKAAAGEFEMTTLSMYQHLQRERADIIRSFNQDLKA

Download         Length: 384 bp

>AT144120 NZ_CP061749:1938688-1938942 [Escherichia coli O15:H12]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6P1S6Q8

Antitoxin

Source ID Structure
AlphaFold DB A0A6P1S5H0

References