144117

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2164710..2165370 Replicon chromosome
Accession NZ_CP046377
Organism Pectobacterium polaris strain PZ1

Toxin (Protein)


Gene name cptA Uniprot ID A0A093S6F1
Locus tag GMX10_RS09970 Protein ID WP_039487287.1
Coordinates 2164957..2165370 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A093SCR9
Locus tag GMX10_RS09965 Protein ID WP_039487284.1
Coordinates 2164710..2164976 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GMX10_RS09945 2160566..2161570 - 1005 WP_039487278.1 substrate-binding domain-containing protein -
GMX10_RS09950 2161625..2162233 - 609 WP_039487279.1 HD domain-containing protein -
GMX10_RS09955 2162634..2163281 + 648 WP_039487281.1 hemolysin III family protein -
GMX10_RS09960 2163473..2164474 - 1002 WP_039487282.1 tRNA-modifying protein YgfZ -
GMX10_RS09965 2164710..2164976 + 267 WP_039487284.1 FAD assembly factor SdhE Antitoxin
GMX10_RS09970 2164957..2165370 + 414 WP_039487287.1 protein YgfX Toxin
GMX10_RS09975 2165439..2166374 + 936 WP_039487289.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
GMX10_RS09980 2166440..2166763 - 324 WP_039487292.1 hypothetical protein -
GMX10_RS09985 2166792..2167310 - 519 WP_039487295.1 flavodoxin FldB -
GMX10_RS09990 2167642..2168029 - 388 Protein_1937 acyl-CoA thioesterase -
GMX10_RS09995 2168254..2169576 - 1323 WP_039487297.1 MHS family MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16297.28 Da        Isoelectric Point: 10.6913

>T144117 WP_039487287.1 NZ_CP046377:2164957-2165370 [Pectobacterium polaris]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQKNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLRAVNGKDKQQLWLASDSMGDEEWRHLRQLLLQQKHWAR

Download         Length: 414 bp

>T144117 NZ_CP061749:970204-970611 [Escherichia coli O15:H12]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCGCAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10489.90 Da        Isoelectric Point: 5.1392

>AT144117 WP_039487284.1 NZ_CP046377:2164710-2164976 [Pectobacterium polaris]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRIISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT144117 NZ_CP061749:969957-970223 [Escherichia coli O15:H12]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTATGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A093S6F1

Antitoxin

Source ID Structure
AlphaFold DB A0A093SCR9

References