Detailed information of TA system TA144115

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 1721101..1722541
• Replicon: chromosome
• Accession: NZ_CP046377
• Organism: Pectobacterium polaris strain PZ1

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: GMX10_RS07905
• Protein ID: WP_161546756.1
• Coordinates: 1721654..1722541 (+)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: A0A6P1S3G1
• Locus tag: GMX10_RS07900
• Protein ID: WP_039483130.1
• Coordinates: 1721101..1721625 (+)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GMX10_RS07885	1718586..1719257	-	672	Protein_1532	DNA damage-inducible protein D	-
GMX10_RS07890	1719334..1720442	+	1109	WP_103164902.1	IS3-like element ISEca11 family transposase	-
GMX10_RS07895	1720459..1720614	-	156	Protein_1534	DNA damage-inducible protein D	-
GMX10_RS07900	1721101..1721625	+	525	WP_039483130.1	hypothetical protein	Antitoxin
GMX10_RS07905	1721654..1722541	+	888	WP_161546756.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
GMX10_RS07910	1722647..1723510	-	864	WP_039483124.1	YicC family protein	-
GMX10_RS07915	1723609..1724517	-	909	WP_039483122.1	LysR family transcriptional regulator	-
GMX10_RS07920	1724731..1725678	-	948	WP_039483119.1	isoaspartyl peptidase/L-asparaginase	-
GMX10_RS07925	1725735..1726556	-	822	WP_039483117.1	M55 family metallopeptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-265)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 34051.03 Da
• Isoelectric Point: 5.7136

>T144115 WP_161546756.1 NZ_CP046377:1721654-1722541 [Pectobacterium polaris]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDFPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIIWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKPIKERTLDNPEYWAYVQGEVHAIASELLNDGIPKNPFDMG

Nucleotide

• Length: 888 bp

>T144115 NZ_CP061749:817844-818140 [Escherichia coli O15:H12]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCACTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19369.51 Da
• Isoelectric Point: 9.0504

>AT144115 WP_039483130.1 NZ_CP046377:1721101-1721625 [Pectobacterium polaris]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSSVLSYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp

>AT144115 NZ_CP061749:818142-818537 [Escherichia coli O15:H12]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A6P1S3G1