Detailed information of TA system TA144102

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 2509994..2510718
• Replicon: chromosome
• Accession: NZ_CP046376
• Organism: Pectobacterium parmentieri strain HC

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: GMW39_RS11715
• Protein ID: WP_161545902.1
• Coordinates: 2510398..2510718 (+)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: GMW39_RS11710
• Protein ID: WP_161545901.1
• Coordinates: 2509994..2510329 (+)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GMW39_RS11680	2505948..2506823	+	876	WP_161545898.1	GTPase family protein	-
GMW39_RS11685	2507187..2507885	+	699	WP_161545899.1	DeoR family transcriptional regulator	-
GMW39_RS11690	2508067..2508636	+	570	WP_161546486.1	hypothetical protein	-
GMW39_RS11695	2508672..2509145	+	474	WP_161545900.1	hypothetical protein	-
GMW39_RS11700	2509162..2509395	+	234	WP_104212404.1	hypothetical protein	-
GMW39_RS11705	2509480..2509954	+	475	Protein_2307	DNA repair protein RadC	-
GMW39_RS11710	2509994..2510329	+	336	WP_161545901.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
GMW39_RS11715	2510398..2510718	+	321	WP_161545902.1	TA system toxin CbtA family protein	Toxin
GMW39_RS11720	2510836..2511669	+	834	WP_161546487.1	DUF4942 domain-containing protein	-
GMW39_RS11725	2511730..2514447	-	2718	WP_161545903.1	DEAD/DEAH box helicase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12092.78 Da
• Isoelectric Point: 4.7468

>T144102 WP_161545902.1 NZ_CP046376:2510398-2510718 [Pectobacterium parmentieri]
MQTSPAIPPRENNPCPSPITVWQQLLTYLLEQHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Nucleotide

• Length: 321 bp

>T144102 NZ_CP061744:c302030-301743 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAACGCACTGGTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCTGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTAGGTTAACAATCAAACCCTCTGGGGATTAA

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12574.24 Da
• Isoelectric Point: 6.4524

>AT144102 WP_161545901.1 NZ_CP046376:2509994-2510329 [Pectobacterium parmentieri]
MSSTETPEWGLKRAVTPRFGARLVQEGNRLHYMADRASFIGTFSKTEAQSLERYFPELIKLLEQKLRTGELNPRQQNCVT
LHCNEWTCEADTLGSVGYVYIVIYPSSAAAE

Nucleotide

• Length: 336 bp

>AT144102 NZ_CP061744:c302339-302037 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
TTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCCGTGGGGGAAGGTATCAGTGAACTGAGGATCC
ACTTTGGCCCGGGCTACAGAGTCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA