144101

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 2182170..2182894 Replicon chromosome
Accession NZ_CP046376
Organism Pectobacterium parmentieri strain HC

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag GMW39_RS10000 Protein ID WP_161545757.1
Coordinates 2182170..2182490 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag GMW39_RS10005 Protein ID WP_161545758.1
Coordinates 2182559..2182894 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GMW39_RS09965 2178345..2178461 - 117 Protein_1967 transposase -
GMW39_RS09975 2179020..2179817 + 798 WP_014699207.1 DgsA anti-repressor MtfA -
GMW39_RS09985 2180177..2180389 + 213 Protein_1969 DUF4102 domain-containing protein -
GMW39_RS09990 2180452..2180667 + 216 WP_161545755.1 transposase -
GMW39_RS09995 2181219..2182052 - 834 WP_161545756.1 DUF4942 domain-containing protein -
GMW39_RS10000 2182170..2182490 - 321 WP_161545757.1 TA system toxin CbtA family protein Toxin
GMW39_RS10005 2182559..2182894 - 336 WP_161545758.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
GMW39_RS10010 2182934..2183407 - 474 WP_161545759.1 DNA repair protein RadC -
GMW39_RS10015 2183505..2183942 - 438 WP_161545760.1 DUF932 domain-containing protein -
GMW39_RS10020 2184060..2185109 - 1050 WP_161545761.1 hypothetical protein -
GMW39_RS10025 2185244..2185585 - 342 WP_161545762.1 hypothetical protein -
GMW39_RS10030 2185959..2186843 - 885 WP_161545763.1 50S ribosome-binding GTPase -
GMW39_RS10035 2186994..2187809 - 816 WP_161545764.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12084.80 Da        Isoelectric Point: 4.5971

>T144101 WP_161545757.1 NZ_CP046376:c2182490-2182170 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCASPIVVWQQLLTYLLEKHYGLTLSDTPFCEEDVIQEHIDAGITLVNAVNFLVERYELVRIDRNGF
SWQEQSPFLTTVDILRARRATGLLKA

Download         Length: 321 bp

>T144101 NZ_CP061725:3578417-3578671 [Micromonospora craniellae]
GTGAAGGTCCAATTCGCCGGCCGAGGCTGGGAAGATTACCTGACCTGGCAACGAGATCGTCAAATGCTCAAACGAGTGAA
CGCCTTGATCGAGGACGTCAGACGCAACGGCCACCAGGGCATCGGCAAACCGGAGCAGCTCCGCGGCAACTGGGCGGGAT
TCTGGTCGAGACGCATCGACCATGAGCACCGCCTCGTATACCGGATCCTGGACGATACAGTGCAGATCGCACAGTGCCGG
TACCACTACGAATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12484.17 Da        Isoelectric Point: 5.8367

>AT144101 WP_161545758.1 NZ_CP046376:c2182894-2182559 [Pectobacterium parmentieri]
MSSTETPEWGLKRTATPQFGARLVQEGNRLHYLADRASIVGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQGCIT
LYCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Download         Length: 336 bp

>AT144101 NZ_CP061725:3578136-3578420 [Micromonospora craniellae]
ATGCGAACCGTTCCTTATTCGGAGGTCAGGCAGAATCTGGCCAAGATGCTCGACCATGTCGTGGACGACGCCGAGGAAGT
GGTGGTGACCCGCTCCGGCCGGGAGGCCGCGGTCATCATCTCGCTGCGCGAGTACGAGTCGTTGAAGGAGACGGCCTACC
TGATGGCCAGCCCCGCCAACGCGCGCCGGCTGAATGAAGCCGTCGAAGATCTGCGCAACGGGGGTGGGGAGATGCGCGAC
CTGATTGACCCCGACGCCAGCTCAGGCGAGGCATCGGCAGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References