144027

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 3288465..3289165 Replicon chromosome
Accession NZ_CP046336
Organism Burkholderia multivorans strain FDAARGOS_719

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag FOC27_RS15550 Protein ID WP_155819766.1
Coordinates 3288465..3288842 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag FOC27_RS15555 Protein ID WP_155824476.1
Coordinates 3288842..3289165 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC27_RS15525 3284005..3284454 + 450 WP_006413500.1 VOC family protein -
FOC27_RS15530 3284558..3286108 - 1551 WP_105777957.1 sodium:solute symporter family protein -
FOC27_RS15535 3286105..3286338 - 234 WP_006398697.1 DUF3311 domain-containing protein -
FOC27_RS15540 3286535..3287452 - 918 WP_059787259.1 hypothetical protein -
FOC27_RS15545 3287680..3287934 + 255 WP_155824475.1 hypothetical protein -
FOC27_RS15550 3288465..3288842 + 378 WP_155819766.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOC27_RS15555 3288842..3289165 + 324 WP_155824476.1 helix-turn-helix domain-containing protein Antitoxin
FOC27_RS15560 3289188..3289679 - 492 WP_155824623.1 DNA-deoxyinosine glycosylase -
FOC27_RS15565 3289676..3290290 - 615 WP_006398690.1 chorismate lyase -
FOC27_RS15570 3290299..3292197 - 1899 WP_039219510.1 molecular chaperone HtpG -
FOC27_RS15575 3292356..3293816 - 1461 WP_105780126.1 PLP-dependent aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(22-114)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13435.42 Da        Isoelectric Point: 9.5721

>T144027 WP_155819766.1 NZ_CP046336:3288465-3288842 [Burkholderia multivorans]
MGINSSMVPYTKPLYWLGSARKDLKAMPEAVQDTFGYALYLAQTGGKHDQAKPLSGFGSAGVLEVVESEDSGTYRAVYTV
KLGGAVYVLHCFQKKSCRGIATPKPDIELVRARLRAAEAHANGGK

Download         Length: 378 bp

>T144027 NZ_CP061642:c48147-47791 [Acinetobacter seifertii]
ATGTGGACAGTCATTACAACGGATCTGTTTAACGAATGGCTTGCACAGCAAGATCAATCTACACAAGAGAAAGTACTCGC
AGCGTTGGTCGTTCTACAGCAACAGGGACCAAGTTTAGGTCGTCCTTTAGTAGATACCGTCTATGACTCCAAATTTACCA
ATATGAAAGACCTACGTGTTCAGCATCGAGGTAAATCACTGAGAGCCTTTTTCGCGTTTGATCCTTTACGACAAGCTATT
GTGCTGTGTATCGGTGATAAAGGTGGTAAAAAGCGTTTTTATAAAGAGATGTTAGATATTGCCGATCAGCAATACGAAAT
TCATCTTTCAACTTTAGGAGATCAATCTAATGGCTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11784.74 Da        Isoelectric Point: 9.1019

>AT144027 WP_155824476.1 NZ_CP046336:3288842-3289165 [Burkholderia multivorans]
MIEIERGSGNVYADLGMPGAEEMRVKAQLAAKIAEIIKTRKWTQQHAARLLGMTQPKLSNMLRGQFRGVSEAKMLDCLAK
LGRDVQIVVGPDRHTEAEGHIEVVFAA

Download         Length: 324 bp

>AT144027 NZ_CP061642:c47798-47496 [Acinetobacter seifertii]
ATGGCTAAGACCCTACAAGAATTATTGGCTAATCGCTCTCCAGAGAGTCAAGCTCGTATTCAACAAATGGCGGATGAATT
ATTGTTGGAAACTCAGCTTCACCTTATTCGTGAAGAGTTAGAGATTTCTCAAAAAGAATTGGCTGCAACCCTTGGAATCA
AACAGCCTTCATTGTCAGCAATCGAAAATCGTGGTCATGATCTTAAAATTTCAACGATGAAAAAGTATGTCGAAGCAATG
GGCGGAAAACTTCGTATTGATGTAGAGCTTCCAACAGGAAAACACATAGGATTCAATGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References