144018

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 4030561..4031230 Replicon chromosome
Accession NZ_CP046329
Organism Shewanella putrefaciens strain FDAARGOS_681

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag FOB89_RS17955 Protein ID WP_041420529.1
Coordinates 4030561..4031001 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag FOB89_RS17960 Protein ID WP_014610118.1
Coordinates 4030982..4031230 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB89_RS17930 4026067..4026540 - 474 WP_011918888.1 SoxR reducing system RseC family protein -
FOB89_RS17935 4026551..4027483 - 933 WP_011918887.1 MucB/RseB C-terminal domain-containing protein -
FOB89_RS17940 4027496..4028116 - 621 WP_011790279.1 anti-sigma factor -
FOB89_RS17945 4028143..4028721 - 579 WP_011790280.1 RNA polymerase sigma factor RpoE -
FOB89_RS17950 4028911..4030524 + 1614 WP_011790281.1 L-aspartate oxidase -
FOB89_RS17955 4030561..4031001 - 441 WP_041420529.1 hypothetical protein Toxin
FOB89_RS17960 4030982..4031230 - 249 WP_014610118.1 succinate dehydrogenase assembly factor 2 Antitoxin
FOB89_RS17965 4031316..4032224 - 909 WP_011790284.1 transcriptional activator NhaR -
FOB89_RS17970 4032332..4032718 - 387 WP_011790285.1 hypothetical protein -
FOB89_RS17975 4032715..4033890 - 1176 WP_011918885.1 Na+/H+ antiporter NhaA -
FOB89_RS17980 4034007..4034801 - 795 WP_011790287.1 thymidylate synthase -
FOB89_RS17985 4034801..4035607 - 807 WP_011790288.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(6-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-78)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17327.51 Da        Isoelectric Point: 8.8774

>T144018 WP_041420529.1 NZ_CP046329:c4031001-4030561 [Shewanella putrefaciens]
VEEQHHSFSVKASFDQRLSLVVFMCVCSSSFLIWPYTEHWLVALLRLGLFLLSVSFLIWQLWRLKDWRLSFMLNGKGDGR
LSTGEHFRILRRTWVTPFVCMIYIDVEENTRLVLLWADMFTGVDYRHLCRLLLKAKMLQAKSQVEI

Download         Length: 441 bp

>T144018 NZ_CP061627:c37632-37276 [Acinetobacter seifertii]
ATGTGGACAGTCATTACAACGGATCTGTTTAACGAATGGCTTGCACAGCAAGATGAATCTACACAAGAGAAAGTACTCGC
AGCGTTGGTCGTTCTACAGCAACAGGGACCAAGTTTAGGTCGTCCTTTAGTAGATACCGTCTATGACTCCAAATTTACCA
ATATGAAAGAGCTACGTGTTCAGCATCGAGGTAAACCACTGAGAGCCTTTTTCGCGTTTGATCCTTTACGACAAGCTATT
GTGCTGTGTATCGGTGATAAAGGCGGTAAAAAGCGTTTTTATAAAGAGATGTTAGATATTGCCGATCAGCAATACGAAAT
TCATCTTTCAACTTTAGGAGATCAATCTAATGGCTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9545.15 Da        Isoelectric Point: 4.5994

>AT144018 WP_014610118.1 NZ_CP046329:c4031230-4030982 [Shewanella putrefaciens]
MELMNIARVRWACRRGMLELDVLFQPFVENIYQDLSDIDKASFIRLLECEDPELFAWFMGHEACPDAELARMVVKVRGRA
AP

Download         Length: 249 bp

>AT144018 NZ_CP061627:c37283-36981 [Acinetobacter seifertii]
ATGGCTAAGACCCTACAAGAATTATTGGCTAATCGCTCTCCAGAGAGTCAAGCTCGTATTCAACAAATGGCGGATGAATT
ATTGTTGGAAACTCAGCTTCACCTTATTCGTGAAGAGTTAGAGATTTCTCAAAAAGAACTGGCTGCAACCCTTGGAATCA
AACAGCCTTCATTGTCAGCAATCGAAAATCGTGGTCATGATCTTAAAATTTCAACGATGAAAAAGTATGTCGAAGCAATG
GGCGGAAAACTTCGTATAGATGTAGAGCTTCCAACAGGAAAACACATAGGATTCAATGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References