Detailed information of TA system TA144017

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /DUF1778(antitoxin)
• Location: 3051506..3052297
• Replicon: chromosome
• Accession: NZ_CP046329
• Organism: Shewanella putrefaciens strain FDAARGOS_681

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FOB89_RS13595
• Protein ID: WP_011919306.1
• Coordinates: 3051506..3052021 (-)
• Length: 172 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FOB89_RS13600
• Protein ID: WP_041420555.1
• Coordinates: 3052022..3052297 (-)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FOB89_RS13585	3049112..3050314	+	1203	Protein_2608	DUF3369 domain-containing protein	-
FOB89_RS13590	3050522..3051481	-	960	WP_011919307.1	site-specific integrase	-
FOB89_RS13595	3051506..3052021	-	516	WP_011919306.1	hypothetical protein	Toxin
FOB89_RS13600	3052022..3052297	-	276	WP_041420555.1	DUF1778 domain-containing protein	Antitoxin
FOB89_RS13605	3052567..3053742	+	1176	WP_011919304.1	DNA-binding protein	-
FOB89_RS13610	3054011..3054979	+	969	WP_011919303.1	arsenic resistance protein	-
FOB89_RS13615	3055197..3056591	-	1395	WP_011919302.1	sensor histidine kinase N-terminal domain-containing protein	-
FOB89_RS13620	3056581..3057249	-	669	WP_011919301.1	response regulator transcription factor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (8-84)

Sequences

Toxin

Protein

• Length: 172 a.a.
• Molecular weight: 18471.58 Da
• Isoelectric Point: 9.5019

>T144017 WP_011919306.1 NZ_CP046329:c3052021-3051506 [Shewanella putrefaciens]
MSLSSAFVLIDAATHDLKGFDCGKPSLNDYLSRFAVRNSSLGLSRTWVLTELVAQGKAPVAAYFTLASSTVTRELLPSQP
KSLPAYPVPVVLLARLGVSLTQQGRQLGAKTLVQALRTALELTDSGLPALGVVLDVLDEAALKFYQHMGLFTPLTDQPMR
LFVPMSTLRQL

Nucleotide

• Length: 516 bp

>T144017 NZ_CP061627:c34037-33849 [Acinetobacter seifertii]
ATGAGTAAAGGACTATTTGAGTTGCGCTTAAAATCTCAAGAAGGTATTGCTCGTGTTATGTATTGCACACTAGTCGGTAA
ACGCATTGTAATGCTCCATAGTTTTGTTAAGAAAACCCAAAAAACACCTAAGCAAGATCTAAACCTAGCACTTGACCGCA
TGAAAGAGGTGAAAAATGCGAACACATGA

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 9999.41 Da
• Isoelectric Point: 5.0890

>AT144017 WP_041420555.1 NZ_CP046329:c3052297-3052022 [Shewanella putrefaciens]
MATALRERIEMRVDAETKQLAERAAAALGCASLTEFMVRLIRDNAPQILQSQSAIEITSAQFDHFQQVCEAAAAPHQRLK
DAAALLDKEGF

Nucleotide

• Length: 276 bp

>AT144017 NZ_CP061627:c33862-33575 [Acinetobacter seifertii]
ATGCGAACACATGAAGAAATGAAAGCACTTGCATTATCTCGTTCAGCAGTGCGTACCGAATACGAACGAATTGAACGTGA
AGAAATGCCCTTGCTCGATATGGTACTTACTGCACTTCGAGAGGCAGGTCTATCCCAAGCGCAAATCGCAGAACGCATGG
GAACAAATGTACCTGCCGTTTCACGGCTAGAAAAAGCATTGATCACAGGCAAACCATCACCATCTATTGCCACATTGCAA
AAATATGCTGCGGCAATTGGTAAACATGTTGAAGTGCGTTTTGTCTAA