Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 3045381..3045952 Replicon chromosome
Accession NZ_CP046329
Organism Shewanella putrefaciens strain FDAARGOS_681

Toxin (Protein)


Gene name parE Uniprot ID A0A2I8S8S5
Locus tag FOB89_RS13575 Protein ID WP_011918375.1
Coordinates 3045641..3045952 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A1Z3MW28
Locus tag FOB89_RS13570 Protein ID WP_011787805.1
Coordinates 3045381..3045641 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB89_RS13545 3040943..3041173 + 231 Protein_2600 hypothetical protein -
FOB89_RS13550 3041671..3043161 + 1491 WP_011787801.1 SulP family inorganic anion transporter -
FOB89_RS13555 3043196..3044050 + 855 WP_011787802.1 universal stress protein -
FOB89_RS13560 3044141..3044473 + 333 WP_011787803.1 TraR/DksA C4-type zinc finger protein -
FOB89_RS13565 3044591..3045211 - 621 WP_011787804.1 recombinase family protein -
FOB89_RS13570 3045381..3045641 + 261 WP_011787805.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FOB89_RS13575 3045641..3045952 + 312 WP_011918375.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOB89_RS13580 3045976..3049056 + 3081 WP_011787830.1 Tn3 family transposase -
FOB89_RS13585 3049112..3050314 + 1203 Protein_2608 DUF3369 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-61)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11862.70 Da        Isoelectric Point: 8.5341

>T144016 WP_011918375.1 NZ_CP046329:3045641-3045952 [Shewanella putrefaciens]
MPVTYHLTPDAQSDLIGIHRFTLAQWGTTQSKTYLSGLRQTIQLLAETPTLGKNRPEVRMNVFSFPYSSHVIYYIQHEHQ
FVVFGILHKSMVPLAHLAEREII

Download         Length: 312 bp

>T144016 NZ_CP061626:c3440155-3439766 [Acinetobacter seifertii]
TTGATCAACCAATTGAATTTTAAACTGAAATATAGCCGTTTCTCGATTATATTTCAGTTTTTTATTGGCTTAAGTTTAGC
AGCTCTGTTTTATCAGTTGATACCAATACTCTGGTGGTTGGTTACGGTCTGTTTATTATTTATAAGTTTTATTTTCTTTT
TAAAGCGACCACAGCTCGTTCAAATTGCTTATTTAGATCAGAAATTATGGTCACTTAGCTTTCATTCAGAACAAACCATT
TCTCGTGTAGAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGGCATAAAACATTAACTTC
TGTGATTTGGTTTGATCAAATGTCCTTATCTCAATGGAAACAGCTTAAGACTTTAGAAAAATTCTATTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9312.71 Da        Isoelectric Point: 6.4546

>AT144016 WP_011787805.1 NZ_CP046329:3045381-3045641 [Shewanella putrefaciens]
MNTLSANEAKIHFGDLLLKAQQAPIQINKNGKPVAVVISADAYQSIETLKLHLLQSKAVKAITDIKMGNLVDGNTFFDEL
AAGQYD

Download         Length: 261 bp

>AT144016 NZ_CP061626:c3440407-3440162 [Acinetobacter seifertii]
ATGACCTTGGAAGAACGTAAAGTAGTTTATCGCGCACGCCGCGGTTTAAAGGAAATTGATGTCTATTTTGACCCGTATGT
GAAAAATTATTATTTAAAGGCAGATCCTGCAGAAAAAGCATTGTTTGCTGAATTAGTAGAGCAGGAAGATCCTGATTTAC
TTGACTGGTTTATGGAAGTATCTGAACCGCCGCGTACAGAATTACGTGATTTTATTCATAAATTAAAGCATTATGTTCAT
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I8S8S5

Antitoxin

Source ID Structure
AlphaFold DB A0A1Z3MW28

References