Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 201555..202105 Replicon chromosome
Accession NZ_CP046329
Organism Shewanella putrefaciens strain FDAARGOS_681

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FOB89_RS00925 Protein ID WP_011918510.1
Coordinates 201806..202105 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FOB89_RS00920 Protein ID WP_011918511.1
Coordinates 201555..201797 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB89_RS00895 196665..197864 + 1200 WP_041420515.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -
FOB89_RS00900 197869..198402 + 534 WP_011918515.1 hotdog family protein -
FOB89_RS00905 198515..199240 + 726 WP_011918514.1 3-ketoacyl-ACP reductase FabG2 -
FOB89_RS00910 199241..200500 + 1260 WP_011918513.1 beta-ketoacyl-ACP synthase -
FOB89_RS00915 200532..201275 + 744 WP_011918512.1 hypothetical protein -
FOB89_RS00920 201555..201797 + 243 WP_011918511.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FOB89_RS00925 201806..202105 + 300 WP_011918510.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOB89_RS00930 202635..203348 - 714 WP_014609649.1 hypothetical protein -
FOB89_RS00935 203708..204184 + 477 WP_011918508.1 GNAT family N-acetyltransferase -
FOB89_RS00940 204235..205422 - 1188 WP_011918507.1 benzoate/H(+) symporter BenE family transporter -
FOB89_RS00945 205586..206152 + 567 WP_011918506.1 XRE family transcriptional regulator -
FOB89_RS00950 206289..206885 - 597 WP_011787674.1 FMN-dependent NADH-azoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-64)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11598.24 Da        Isoelectric Point: 8.8270

>T144012 WP_011918510.1 NZ_CP046329:201806-202105 [Shewanella putrefaciens]
MNNKRYKLSRLSQTHLQQIKDYTLQHFSESQWHKYKESLISGLQMLADNPGLGRSCEDIYPNGFYFPIAKHTAYFTKEDD
FILIVALLGQPQLPQNHLK

Download         Length: 300 bp

>T144012 NZ_CP061616:c35990-35715 [Acinetobacter seifertii]
ATGTTAATCGTTGAGTGGACACCCAACGCTATTGAGGATTTAGAAGCAATTTCAGACTATATAGCTGAACACAATCCTAT
TGCTGCATACAACTTGGAAGATCACATTCTAAAATGCGCTGAAAGCCTATCAGAACATCCATATAAGGGTGTTTCTGGAC
GTGTAGTGGGTACAAGGGAAATGCTGGTACACCCGAACTACTGGCTGATTTATGAAGTCTCAGACATGATCAAAATCAAA
GGCGTACTTCATACTAGAAAATCATATCCGGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8936.14 Da        Isoelectric Point: 5.0758

>AT144012 WP_011918511.1 NZ_CP046329:201555-201797 [Shewanella putrefaciens]
VQTLTANEAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Download         Length: 243 bp

>AT144012 NZ_CP061616:c36165-35977 [Acinetobacter seifertii]
ATGAATACCGTTTTCGATCCTATAGTGTCTGAGTTTGACAGCTCTGATCATGAATCTGAATATAATGCATGGTTCAAAGC
GAAAATTGAAAAATCAATGGCTGATACACGTCCAACTGTACCACACGACCAGGTAGTAGCACGTTTAAAAAAACGTCGTG
AGGAAAGAACAACTAATGTTAATCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References