Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3907023..3907677 Replicon chromosome
Accession NZ_CP046320
Organism Gordonia bronchialis strain FDAARGOS_676

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FOB84_RS18125 Protein ID WP_052298363.1
Coordinates 3907258..3907677 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FOB84_RS18120 Protein ID WP_083775533.1
Coordinates 3907023..3907268 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB84_RS18090 3903465..3904307 - 843 Protein_3580 GTPase -
FOB84_RS18095 3904316..3904609 + 294 WP_012833032.1 hypothetical protein -
FOB84_RS18100 3904646..3904999 + 354 WP_012833031.1 hypothetical protein -
FOB84_RS18105 3905160..3905534 + 375 WP_012833030.1 VOC family protein -
FOB84_RS18110 3905696..3905983 + 288 WP_012833029.1 hypothetical protein -
FOB84_RS18115 3906108..3906988 + 881 Protein_3585 putative DNA binding domain-containing protein -
FOB84_RS18120 3907023..3907268 + 246 WP_083775533.1 hypothetical protein Antitoxin
FOB84_RS18125 3907258..3907677 + 420 WP_052298363.1 PIN domain-containing protein Toxin
FOB84_RS18130 3907688..3908788 - 1101 WP_012833026.1 epoxide hydrolase -
FOB84_RS18135 3908886..3909320 + 435 WP_012833025.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15188.41 Da        Isoelectric Point: 6.2135

>T144007 WP_052298363.1 NZ_CP046320:3907258-3907677 [Gordonia bronchialis]
MLLDINVLVALSWDQHVHHGVAHERFAQLTEWSTCPVTEAGLVRVLMTESAVGRVVTGAEALGQLAALRTVTGWGFLHDD
ASLADSVIDLRVLMGRRQVTDLHLVNLAARNGRKLATFDAGLRESLVPADRAWVEVWSA

Download         Length: 420 bp

>T144007 NZ_CP061603:482773-483162 [Acinetobacter seifertii]
TTGATCAACCAATTGAATTTTAAACTGAAATATAGCCGTTTCGCGATTGTATTTCAGTTTTTTATTGGCCTATGTTTAGC
AGCTCTGTTTTATCAGCTGATACCAATACTCTGGTGGTTGGTTACGCTCTGTTTATTATTTATAAGTTTTATTTTCTTTT
TAAAGCGACCACAGCTCGTTCAAATTGCCTATTTAGATCAGAAATTATGGTCTCTTAGCTTTCATTCAGAACAAACCATT
TCTCGTGTAGAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGGTCTATTTTAAGGGTGATAAAACATTAACTTC
TGTTATTTGGTTTGATCAAATGTCCTTATCTCAATGGAAACAGCTTAAGACTTTAGAAAAATTCTATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8087.99 Da        Isoelectric Point: 4.6140

>AT144007 WP_083775533.1 NZ_CP046320:3907023-3907268 [Gordonia bronchialis]
VRTTLDLDPVVLSAARAKAKADGISLGKAVSELARAGLSAPRSAAATSAPSGFPVLTGVPGHPVTDDAVAEYRDDDVTDA
S

Download         Length: 246 bp

>AT144007 NZ_CP061603:482521-482766 [Acinetobacter seifertii]
ATGACCTTGGAAGAACGTAAAGTAGTTTATCGCGCACGCCGCGGTTTAAAGGAAATTGATGTCTATTTTGACCCGTATGT
GAAAAATTATTATTTAAAGGCAGATCCAGCAGAAAAAGCATTGTTTGCTGAATTAGTAGAGCAGGAAGATCCTGATTTAC
TTGACTGGTTTATGGAAGTATCTGAACCGCCGCGTACAGAATTACGTGATTTTATTCATAAATTAAAGCATTATGTTCAT
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References