Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 20023..20941 Replicon plasmid unnamed1
Accession NZ_CP046318
Organism Campylobacter coli strain FDAARGOS_735

Toxin (Protein)


Gene name Fic Uniprot ID -
Locus tag FOC43_RS08715 Protein ID WP_002779836.1
Coordinates 20023..20706 (-) Length 228 a.a.

Antitoxin (Protein)


Gene name Fti Uniprot ID -
Locus tag FOC43_RS08720 Protein ID WP_002779838.1
Coordinates 20699..20941 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC43_RS08680 15077..15400 - 324 WP_002790618.1 hypothetical protein -
FOC43_RS08685 15590..15958 + 369 WP_002779826.1 hypothetical protein -
FOC43_RS08690 15936..18092 + 2157 WP_002779827.1 relaxase/mobilization nuclease domain-containing protein -
FOC43_RS08695 18131..18355 - 225 WP_002779829.1 hypothetical protein -
FOC43_RS08700 18358..19044 - 687 WP_002779831.1 AAA family ATPase -
FOC43_RS08705 19092..19487 - 396 WP_002779833.1 conjugal transfer protein TraM -
FOC43_RS08710 19551..20018 - 468 WP_002779834.1 signal peptidase I -
FOC43_RS08715 20023..20706 - 684 WP_002779836.1 Fic family protein Toxin
FOC43_RS08720 20699..20941 - 243 WP_002779838.1 hypothetical protein Antitoxin
FOC43_RS08725 21185..21640 + 456 WP_155820423.1 IS200/IS605 family transposase -
FOC43_RS08730 21653..22903 + 1251 WP_032685593.1 transposase -
FOC43_RS08735 22954..23673 - 720 WP_002784845.1 conjugal transfer protein TraL -
FOC43_RS08740 23684..25507 - 1824 WP_002779800.1 type IV secretory system conjugative DNA transfer family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..38104 38104


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(60-169)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 228 a.a.        Molecular weight: 25919.05 Da        Isoelectric Point: 10.1133

>T144004 WP_002779836.1 NZ_CP046318:c20706-20023 [Campylobacter coli]
MIDKVLKFLDDGIPKNDFDRQLLASNLVGATNLIELNKKERIITLQAAKKLELNPIKGNFDYQHLKDIHKALFKDVYTWA
GKDRMEVGLHGNFGKYAPNGAIINFVPGKELDKYSKIIFDELAKNNYLKNSKDLNHFAKNLAKFMGEINALHPFREGNGR
TQRIFLNELAKNAGYKLDLNLISKHKMIHACVEASQLKPGRLEALIKDNLKNFRQNLDLEQNKGMSL

Download         Length: 684 bp

>T144004 NZ_CP061585:c36129-35770 [Acinetobacter seifertii]
ATGGCTTGGGATGTAGAAACAACAGAACTTTTTGATTCTTGGTTGGCAGAACAAGATGAAAATGCTCAAGATAAAATCTT
AGCGTCTTTGCTTGTTTTGTCAGAACTGGGGCCAAATCTAGGCCGGCCTCATGTTGATACTATTAAAGAATCAAAATATC
CGAACATGAAAGAGATACGTGTGCAAGTTAAAGGTCATCCGATCCGTGGTTTCTTTGCATTTGATCCAGAACGTAAAGCC
ATTGTTTTGTGTGCTGGAGATAAGAAAGGGCTAAATGAAAAAGCCTTTTATAAAGAAATGATCAAGATTGCAGATGAACA
ATATGAGCAATATTTACGTGATAATTACGGAGATAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9478.72 Da        Isoelectric Point: 4.2508

>AT144004 WP_002779838.1 NZ_CP046318:c20941-20699 [Campylobacter coli]
MQKQYPEVYSLEESLAILKKYKDDLTKEQYEQNKSIICGFAIENMFANEEDIINLIKVDKQEKTPDEIIAEYKKEWGVND

Download         Length: 243 bp

>AT144004 NZ_CP061585:c35770-35471 [Acinetobacter seifertii]
ATGGCTAAATTAAACGATATAATTTCAAAACGCTCACCTGAAAGCCAACAACGCATCAAGAAAATGGCAAATCAAATGCT
ATTGGATATTAACCTATCGAACCTACGGGAAGAGTTAAAAATATCTCAAGCTGAAATTGCAAAAAATCTAGGTGTAAGCC
AAGCTGCTATTTCAAAACGTGAAAAATTAGGTAAAGATCTTAAGATTTCATCATTAAAAGAATATGTTGAAGCTATGGGT
GGCAAAGTAAGGTTAGATGTTGAGTTACCTAACGGAAAGCATGTTGCTATATCTATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References