Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3363324..3363859 Replicon chromosome
Accession NZ_CP046293
Organism Yersinia intermedia strain FDAARGOS_730

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FOC38_RS15710 Protein ID WP_032905972.1
Coordinates 3363324..3363611 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0T9M846
Locus tag FOC38_RS15715 Protein ID WP_032905973.1
Coordinates 3363608..3363859 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC38_RS15690 3358636..3359562 + 927 WP_005183819.1 oxygen-dependent coproporphyrinogen oxidase -
FOC38_RS15695 3359562..3360017 + 456 WP_032905970.1 YaiI/YqxD family protein -
FOC38_RS15700 3360104..3362383 - 2280 WP_005183822.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
FOC38_RS15705 3362719..3363294 - 576 WP_032906016.1 GDP-mannose pyrophosphatase NudK -
FOC38_RS15710 3363324..3363611 - 288 WP_032905972.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOC38_RS15715 3363608..3363859 - 252 WP_032905973.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FOC38_RS15720 3363990..3364589 - 600 WP_005183830.1 cytochrome c-type protein NapC -
FOC38_RS15725 3364618..3365085 - 468 WP_032905974.1 nitrate reductase cytochrome c-type subunit -
FOC38_RS15730 3365181..3367676 - 2496 WP_032905975.1 nitrate reductase catalytic subunit NapA -
FOC38_RS15735 3367673..3367939 - 267 WP_032905977.1 chaperone NapD -
FOC38_RS15740 3367929..3368432 - 504 WP_032905979.1 ferredoxin-type protein NapF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11130.05 Da        Isoelectric Point: 10.3510

>T143849 WP_032905972.1 NZ_CP046293:c3363611-3363324 [Yersinia intermedia]
MTYAVKFREEALKEWHKLDKTIQQQFAKKLKKCSDNPHIESAKLRGMKNCYKIKLRSSGFRLVYEIIDDVLIVAVVAVGK
RDRSEVYNLASDRLR

Download         Length: 288 bp

>T143849 NZ_CP061381:85162-85446 [Klebsiella pneumoniae]
ATGACCTATAAGCTGGCTTTCAACGAATCCGCTCTGAAAGAATGGAAGAAGCTGGGTCATACACTACAGGTACAGTTCAA
AAAGAAACTCAAAGAGCGCCTGGAGAACCCCAGAGTTCCGGCATCACAGCTACATGGACGTAAGGACCAGTATAAAATTA
AGCTACGTGGTGCCGGATATCGCCTTGTCTATCGTGTAGAGGACGACATTGTCACAGTCACTGTTATCGGCGTAGGCAAA
CGCGAAAACGACGACATTTATAATGCAACCCTTAATCGCAATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.56 Da        Isoelectric Point: 4.3287

>AT143849 WP_032905973.1 NZ_CP046293:c3363859-3363608 [Yersinia intermedia]
MPSIILTDTSASVSELKKNPMATVNAGAGFPVAILNRNQPAFYCVPAELYEQIMEALDDHELAELVNRRRHQPLLDIDLD
SYL

Download         Length: 252 bp

>AT143849 NZ_CP061381:84924-85172 [Klebsiella pneumoniae]
ATGGCATTTCAGGTTCTGACCACTACAGCAGCTAGCATTACTGAACTTAAACGTGACCCTATGGGTACTTTCCACGCCGG
GGATGGCGCTCCGGTAGCCATTCTTAATCGTAATGAGCCTGCATTCTACTGTGTGCCACCGGCACTCTATGCCCAGTTGA
TGGAGCTTCTGGAAGATGAAGAGCTGGGACGGATGGCTGATGAGCGAAGCGGAGAAAAGGTTATAGAGGTCAATATTGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0T9M846

References