Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 259756..260720 Replicon chromosome
Accession NZ_CP046293
Organism Yersinia intermedia strain FDAARGOS_730

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag FOC38_RS01250 Protein ID WP_155967532.1
Coordinates 260313..260720 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag FOC38_RS01245 Protein ID WP_155967530.1
Coordinates 259756..260316 (+) Length 187 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC38_RS01225 256837..258210 + 1374 WP_155967524.1 hypothetical protein -
FOC38_RS01230 258210..258845 + 636 WP_155967526.1 tail fiber assembly protein -
FOC38_RS01235 258901..259146 - 246 WP_155967528.1 DinI-like family protein -
FOC38_RS01240 259157..259399 - 243 WP_155967969.1 hypothetical protein -
FOC38_RS01245 259756..260316 + 561 WP_155967530.1 SocA family protein Antitoxin
FOC38_RS01250 260313..260720 + 408 WP_155967532.1 hypothetical protein Toxin
FOC38_RS01255 260741..261829 - 1089 WP_155967534.1 site-specific integrase -
FOC38_RS01260 261919..262968 + 1050 WP_155967536.1 tRNA dihydrouridine(20/20a) synthase DusA -
FOC38_RS01265 263283..263501 + 219 WP_005191465.1 envelope stress response protein PspG -
FOC38_RS01270 263791..264774 - 984 WP_005191463.1 quinone oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 214262..283043 68781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(27-140)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15333.68 Da        Isoelectric Point: 6.7306

>T143834 WP_155967532.1 NZ_CP046293:260313-260720 [Yersinia intermedia]
MTEAYDPYRKGTVLAPSGPHNHLHIICSDPIYNQEFGCDCVLVVNICSIPTSGIHDPACVLQAGEHAFIKHPSYLLYRLS
VLWRVPVLCNKVDSGEYKTYDDINELTFKKIIQGFSDSDFTPFKIVRFIEKNKLI

Download         Length: 408 bp

>T143834 NZ_CP061379:5767100-5767525 [Bradyrhizobium genosp. B]
GTGAACCTGCTGCTTGATACCAACGTGCTGTCCGAGGTTCAGCGACCGATGCCCTCTCCCAAGGTCTTGGCATGGCTTGA
TACGATCGACGAGGATCGCGCGTTCATTAGTGTAGCCTCGATTGCCGAACTTCGCCGTGGCATCGCATTACTGGAGGATG
GCCGCCGGCGCACGGCGCTGGCCACCTGGTTGGCTCACGATCTACCAGAGCGTTTTGCCGGGCGCATGCTGCCGATCGAC
CACGCTGTGGCTGAGCGCTGGGGTGACCTGATGGCGGAGAGCCGCAGAAGCGGCGTCGCGCTATCGGTCATCGACGGCTT
CTTTGCCGCCACCGCACTTGCAAATGGCCTCACGCTCGTCACGCGTAATGTAAAGGATTTTGCAGCATTCGGCGTGCAGC
TATTCAATCCCTGGGACGACGTATAG

Antitoxin


Download         Length: 187 a.a.        Molecular weight: 21605.76 Da        Isoelectric Point: 5.6710

>AT143834 WP_155967530.1 NZ_CP046293:259756-260316 [Yersinia intermedia]
MFSEERVAQMAAYLLHKRGGRMAYLKLMKLLYLSDRQSMEMYGEPISGDRYVSMDKGPVLSRTLSLITGGGDVPNHGWDK
WIRGERDHNVSLKIKFEDLSDLDELCRADMKAMDAIYEKYGHWNRFDLCEQTHRICPEWQDPDGSSIPIKTKDIFMALGK
DVNEAEELTRILQDRDQLVKMTLDLR

Download         Length: 561 bp

>AT143834 NZ_CP061379:5766822-5767103 [Bradyrhizobium genosp. B]
ATGACAGATCACAGCACCGCGCCCGATTCACCCGCGACGGATACGTGGACGCTTGCCAATGCCAAGGCACGACTGTCCGA
AGTGATCGACCGTGCCCAAACCGGCCCCCAGATCATCACCCGCCATGGCAAGCCGAATGCCGTGGTCGTTTCCGCGGAGG
AATGGTCGCGCAAGACCGCGCGCAAAGGCACGCTGGCCGAATTCCTGCTGGCCTCTCCGCTGCACGGGGCCGACCTCAAG
CTTGAACGCATGCACGACGTCCCCCGCGACGAGATGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References