Detailed information of TA system TA143811

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 23023..23648
• Replicon: plasmid unnamed1
• Accession: NZ_CP046282
• Organism: Salmonella enterica strain FDAARGOS_687

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FOB95_RS00130
• Protein ID: WP_000911322.1
• Coordinates: 23250..23648 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: FOB95_RS00125
• Protein ID: WP_000450265.1
• Coordinates: 23023..23250 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FOB95_RS00125	23023..23250	+	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin
FOB95_RS00130	23250..23648	+	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
FOB95_RS00135	23657..25819	-	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
FOB95_RS00140	26196..26927	-	732	WP_000782438.1	complement resistance protein TraT	-
FOB95_RS00145	26963..27457	-	495	WP_010999946.1	entry exclusion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..94642	94642

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-92)

Antitoxin

• Antitoxin ParD (6-63)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 17065.17 Da
• Isoelectric Point: 12.9205

>T143811 WP_000911322.1 NZ_CP046282:23250-23648 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 399 bp

>T143811 NZ_CP061369:3553959-3554258 [Komagataeibacter rhaeticus]
ATGCCGACCTGTAGAAAGACACGGCTCGCCGAAGACGACATCGTCAACATCTATATGCAGGGCGTGAGGGATTTCGGGCC
GCGGCAGGCCGAAATCTACCATGCAGGGCTGTCGGACGCGTTCGACCTTATCGCCTCACATCCGCAGCTTGCGCCTGAAC
GTCACGAATTCGACCCACCGATACGGCTGCACCGTCATCGGGCTCACCATATCCTCTATCTCATTGACGACGATGGGGTT
CTGATCGTCCGCGTGCTGCCCCGACTACGGCGCTGGGAGCGGCTTATGGAAACAGACTGA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 9759.25 Da
• Isoelectric Point: 12.6750

>AT143811 WP_000450265.1 NZ_CP046282:23023-23250 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 228 bp

>AT143811 NZ_CP061369:3553718-3553972 [Komagataeibacter rhaeticus]
ATGGCAACAATGAACGTATCCCTGCCCGATCCCATGAAGGAATGGGTAGAGGCTCAGGCCAAAACGGGACGCTACAGCAA
TGCAAGCGACTATGTCCGCGACCTGATCCGGCGTGATCAGGAGGCCCGTGCGGCGCATGATGAGGTTCAGGCCCACATCA
CGGCCGGTCTGCGTAGTGGCGTCGGGACCAGGAGCATGAAGCAGTTGCTGCAGGATGCTCGCGCGGCTGCCGGGACGACG
GATGCCGACCTGTAG