Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 879082..879589 Replicon chromosome
Accession NZ_CP046269
Organism Vibrio spartinae strain 3.6

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag Vspart_RS20390 Protein ID WP_182288783.1
Coordinates 879082..879351 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Vspart_RS20395 Protein ID WP_182288784.1
Coordinates 879344..879589 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Vspart_RS20365 875038..875838 - 801 WP_159439430.1 signal peptidase I -
Vspart_RS20370 875891..876637 - 747 WP_182288781.1 carbon-nitrogen hydrolase family protein -
Vspart_RS20375 876675..877553 - 879 WP_139302083.1 alpha/beta hydrolase fold domain-containing protein -
Vspart_RS20380 877987..878376 - 390 WP_182289163.1 GNAT family N-acetyltransferase -
Vspart_RS20385 878437..878940 - 504 WP_182288782.1 peptide deformylase -
Vspart_RS20390 879082..879351 - 270 WP_182288783.1 Txe/YoeB family addiction module toxin Toxin
Vspart_RS20395 879344..879589 - 246 WP_182288784.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Vspart_RS20400 879736..880191 - 456 WP_074371256.1 hypothetical protein -
Vspart_RS20405 880330..880806 - 477 WP_074371257.1 GNAT family N-acetyltransferase -
Vspart_RS20410 880882..881352 - 471 WP_074371258.1 dual specificity protein phosphatase family protein -
Vspart_RS20415 881490..882128 - 639 WP_139302084.1 hypothetical protein -
Vspart_RS20420 882261..882863 - 603 WP_074371260.1 hypothetical protein -
Vspart_RS20425 883022..883495 - 474 WP_182288785.1 GrpB family protein -
Vspart_RS20430 883601..884179 - 579 WP_074371262.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10580.02 Da        Isoelectric Point: 8.4804

>T143794 WP_182288783.1 NZ_CP046269:c879351-879082 [Vibrio spartinae]
MSSSQRLLSWTDESWNDRLYWQIQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYAVDDQAI
TIISCCYHY

Download         Length: 270 bp

>T143794 NZ_CP061368:c874941-874513 [Wenzhouxiangella sp. AB-CW3]
GTGAGTAGCCGCTTTCGCTACCTGCTCGACACCAATATCATTTCCGACCTGGTGCGCCATCCGCAAGGCCCGGTCGCCCA
TCGCATCTCCGAGCTGGGGGAGGACACGGTCTGTACAAGTATCGTGGTTTCCGCCGAGCTGCGATACGGTGCGGCGAAAT
CCGGATCGGAGAAACTGGCTCACCGAGTCGAACTGCTGCTTTCGGCCCTGGAAATTCTACCGCTCGAATCCCCGGCCGAT
CACCACTATGCAGAACTCCGTGATCATCTGACCCGCCAGGGAACCCTCATCGGTCCCAATGACTTGCTGATCGCCGCTCA
TGCGCTGGCTATGGGCATGACAATCGTGACCGCAAACGAACGCGAGTTCTTGCGAGTCCCTGGACTTGGGGTCGAGAACT
GGCTGCCTGGTTCGGATCGGGACAGGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8997.08 Da        Isoelectric Point: 5.0197

>AT143794 WP_182288784.1 NZ_CP046269:c879589-879344 [Vibrio spartinae]
MKIVSFTEARNSLKAVLDGVVNDADTTVITRRDAEDAVVMSYNSLMETVHLLRSPENAGHLNRSISQYRAGQTTARDLMD
E

Download         Length: 246 bp

>AT143794 NZ_CP061368:c875180-874938 [Wenzhouxiangella sp. AB-CW3]
ATGACGACATCGGAACGACAGGTGCGACTGTTCCGCAACGGGCGCAACCAGGCATTGCGTATTCCCCGCGAGTTCGAACT
GGAAGGCGACGAGGCCATCCTGCACAAGGAAGGTGATCGGCTGATCATCGAGCCGGTTCGCAAGGGCAAGCTGCTGGCCC
TGCTGGCCTCGCTCGAGCCACTGGATGTGCCGTTTCCGGACGTGGACGAGGATCTGCCTGAACTGGACGACGATGCATTG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References