Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1293390..1293949 Replicon chromosome
Accession NZ_CP046268
Organism Vibrio spartinae strain 3.6

Toxin (Protein)


Gene name relE Uniprot ID A0A1N6M707
Locus tag Vspart_RS05785 Protein ID WP_074373718.1
Coordinates 1293390..1293668 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1N6M774
Locus tag Vspart_RS05790 Protein ID WP_074373719.1
Coordinates 1293668..1293949 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Vspart_RS05765 1288461..1289402 - 942 WP_074373714.1 diguanylate cyclase -
Vspart_RS05770 1289732..1290886 - 1155 WP_182288389.1 PLP-dependent aminotransferase family protein -
Vspart_RS05775 1291028..1291897 + 870 WP_074373716.1 AraC family transcriptional regulator -
Vspart_RS05780 1292132..1292884 + 753 WP_074373717.1 methyltransferase domain-containing protein -
Vspart_RS05785 1293390..1293668 - 279 WP_074373718.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
Vspart_RS05790 1293668..1293949 - 282 WP_074373719.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
Vspart_RS05795 1294340..1294669 + 330 WP_182288390.1 antibiotic biosynthesis monooxygenase -
Vspart_RS05800 1295856..1297376 + 1521 WP_182288613.1 SIR2 family protein -
Vspart_RS05805 1297431..1297754 + 324 WP_182288391.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10979.51 Da        Isoelectric Point: 4.2597

>T143792 WP_074373718.1 NZ_CP046268:c1293668-1293390 [Vibrio spartinae]
MIYWEEESLNDREKIFEFLYDFNPDVAERTDDIIEAKVENLNDQPLMGVQRDGIRGRLLIISEVSMIVSYFVDDSNIRIM
RVLHQKQKFPIE

Download         Length: 279 bp

>T143792 NZ_CP061368:c184295-184044 [Wenzhouxiangella sp. AB-CW3]
ATGTCCACGATTAGCTACACTGATCTGCGCCGCCGGCTGGCCAGCGCCATGGACCAGGTCAACGAAGACCATGCGCCGCT
CTACATCACCCGCCAGAAGGGCAAGGGGGCGGTGTTGCTTTCGGCGGATGATTACGCCTCGATCGAGGAGACGTTGTACC
TGATGTCCAGCCCGCGCAATGCCGCGCGGTTGACCGAAGCGATCGAGGGTTTGCGGCAAGGCGAAGGTGAAACGCGCGAA
CTGATCGAGTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10751.03 Da        Isoelectric Point: 9.2520

>AT143792 WP_074373719.1 NZ_CP046268:c1293949-1293668 [Vibrio spartinae]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKALSHDGWLTEQVNLAFDKFDSGRAVFVDHESAKNR
MAARKAKIRNRGQ

Download         Length: 282 bp

>AT143792 NZ_CP061368:c184047-183793 [Wenzhouxiangella sp. AB-CW3]
GTGAAGATCTGTTTTCATGCACACGCCTGGGCTGATTATCTCTATTGGCAGAAGGCCGACCCGAAAAAACTCAAGCGCAT
CAACGAACTGATCCGTGCCATTGGTCGTGACCCGTTCAAGGGTGTTGGCAAGCCGGAGCCACTGAGAGGAAACTGGTCGG
GCTTCTGGTCGCGCCGGATTGATCGGAAACATCGGCTGGTCTATGCCGTCGAGAACGACACGCTGCTGATTGCCCAGTGC
CGGTTTCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1N6M707

Antitoxin

Source ID Structure
AlphaFold DB A0A1N6M774

References