Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 272739..273298 Replicon chromosome
Accession NZ_CP046252
Organism Sphingobium sp. CAP-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GL174_RS01325 Protein ID WP_155178511.1
Coordinates 272739..273032 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GL174_RS01330 Protein ID WP_155178512.1
Coordinates 273029..273298 (-) Length 90 a.a.

Genomic Context

GL174_RS01310GL174_RS01335GL174_RS01345GL174_RS01315GL174_RS01320GL174_RS01325GL174_RS01330GL174_RS01340
Location: 268296..270359 (2064 bp)
Type: Others
Protein ID: WP_155178508.1
Location: 273983..276058 (2076 bp)
Type: Others
Protein ID: WP_155178514.1
Location: 276900..277666 (767 bp)
Type: Others
Protein ID: WP_155178518.1
Location: 270680..272359 (1680 bp)
Type: Others
Protein ID: WP_155178509.1
Location: 272378..272626 (249 bp)
Type: Others
Protein ID: WP_155178510.1
Location: 272739..273032 (294 bp)
Type: Toxin
Protein ID: WP_155178511.1
Location: 273029..273298 (270 bp)
Type: Antitoxin
Protein ID: WP_155178512.1
Location: 276507..276821 (315 bp)
Type: Others
Protein ID: WP_155178516.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GL174_RS01310268296..270359+2064WP_155178508.1hypothetical protein-
GL174_RS01315270680..272359-1680WP_155178509.1recombinase family protein-
GL174_RS01320272378..272626-249WP_155178510.1hypothetical protein-
GL174_RS01325272739..273032-294WP_155178511.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GL174_RS01330273029..273298-270WP_155178512.1ribbon-helix-helix domain-containing proteinAntitoxin
GL174_RS01335273983..276058+2076WP_155178514.1ParB/RepB/Spo0J family partition protein-
GL174_RS01340276507..276821-315WP_155178516.1hypothetical protein-
GL174_RS01345276900..277666+767WP_155178518.1IS5 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--192078..298383106305


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11456.17 Da        Isoelectric Point: 8.0506

>T143751 WP_155178511.1 NZ_CP046252:c273032-272739 [Sphingobium sp. CAP-1]
MRIKWTGKASLDLVRLHEHLRPVAPEAAARVVQQLARAPDRLLEYPRIGEKLDAYSPREVRRIIVGNYELRYEIADATIF
ILRLWHCREERSFESDD

Download         Length: 294 bp

>T143751 NZ_CP061341:c1098181-1097912 [Lactobacillus kefiranofaciens]
ATGATTTTAAAATATCATGGCAGGATTAAAAACTCAGCTAAGCCTGATTTAAAGAAGATTAAGCGAAGTAATCTGAAAGA
TAATTTTCAAGATATTATAGATCAACTCAAAAAAGATCCTTATAAAAAGAATCAAGGATTTGAAAAATTAGAACCACCAA
TTTTAGGAAAATATTCTCGAAGAATCAATATAAAACATCGAGTTGTTTATACTGTTGATGATGTTAATAAGATAGTAAGT
ATTTACTCGGCCTGGTCACATTATGAATGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9800.14 Da        Isoelectric Point: 4.6239

>AT143751 WP_155178512.1 NZ_CP046252:c273298-273029 [Sphingobium sp. CAP-1]
MAIETKVLTAHVPLGLAEKVEAMASRLERSRGWVMKQALAAWVDQEEERHRMTLEALDDVDAGRVIDHQAIQAWADSLGT
DTPLPPPSA

Download         Length: 270 bp

>AT143751 NZ_CP061341:c1098444-1098178 [Lactobacillus kefiranofaciens]
ATGGATGCAACAATTTATACTCCCACAGGAGCAAGACGTAATTTATTCAATCTTATCAAGCAAGTTAATAAAAACCATAT
TCCAGTTAATATTGAATCTACAAAAGATAAAGCAGAAAGTGCTGTGTTAATAAGTAAATCCGACTGGGACGCTATTCAGG
AGACTCTTTATCTTGAGTCCAATGGTGTAGGAGAAGTTGTGAGAAAACGTGAAAAGGACAATTCAGGTTTTACTGATATT
GATGATATTAACTGGGATGAGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References