Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 3228250..3228815 Replicon chromosome
Accession NZ_CP046155
Organism Leptolyngbya sp. BL0902

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFS31_RS14290 Protein ID WP_198805448.1
Coordinates 3228471..3228815 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GFS31_RS14285 Protein ID WP_198808226.1
Coordinates 3228250..3228474 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFS31_RS14255 3224013..3224513 + 501 WP_198805441.1 Photosystem I reaction center subunit III -
GFS31_RS14260 3224562..3224684 + 123 WP_190494970.1 photosystem I reaction center subunit IX -
GFS31_RS14265 3224908..3225393 + 486 WP_198805442.1 photosystem I reaction center subunit XI -
GFS31_RS14270 3225558..3226022 - 465 WP_198805444.1 carboxypeptidase regulatory-like domain-containing protein -
GFS31_RS14275 3226321..3227529 + 1209 WP_198805445.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
GFS31_RS14280 3227736..3228098 + 363 WP_198805446.1 hypothetical protein -
GFS31_RS14285 3228250..3228474 + 225 WP_198808226.1 DUF433 domain-containing protein Antitoxin
GFS31_RS14290 3228471..3228815 + 345 WP_198805448.1 DUF5615 family PIN-like protein Toxin
GFS31_RS14295 3228907..3231066 - 2160 WP_198805449.1 AMIN domain-containing protein -
GFS31_RS14300 3231153..3232052 - 900 WP_198805450.1 hypothetical protein -
GFS31_RS14305 3232052..3232834 - 783 WP_198805452.1 PilN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12917.00 Da        Isoelectric Point: 4.1478

>T143692 WP_198805448.1 NZ_CP046155:3228471-3228815 [Leptolyngbya sp. BL0902]
MKIWVDAQPPPTLANWLSDTFSVEAYALRELSLRDAKDIEIFEAARSEGAIILTKDSDFIDLVCRLGIPPQILWLTCGNV
TNRNLRQLLMLTLPEALEQLNQEMMMIEIGNINS

Download         Length: 345 bp

>T143692 NZ_CP061329:2352485-2353807 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CAGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTCATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTTAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCTGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCGTTTTTGATGGGGTCCAGCGAGGCGCTTCGCGATCGTTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGATGGACATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTAAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8166.52 Da        Isoelectric Point: 4.9428

>AT143692 WP_198808226.1 NZ_CP046155:3228250-3228474 [Leptolyngbya sp. BL0902]
MSSLLSRITQTPGQCGGKPCIRGMRIRVADILEMLAENVSSTEILENFPDLELADIQACLIFAARRTDFPRLTA

Download         Length: 225 bp

>AT143692 NZ_CP061329:2352219-2352485 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACACTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References