Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 2030154..2030716 Replicon chromosome
Accession NZ_CP046155
Organism Leptolyngbya sp. BL0902

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFS31_RS09000 Protein ID WP_198807834.1
Coordinates 2030375..2030716 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GFS31_RS08995 Protein ID WP_198807833.1
Coordinates 2030154..2030378 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFS31_RS08975 2027626..2028999 + 1374 WP_198807829.1 hypothetical protein -
GFS31_RS08980 2029269..2029544 + 276 WP_198807830.1 hypothetical protein -
GFS31_RS08985 2029541..2029801 + 261 WP_198807831.1 hypothetical protein -
GFS31_RS08990 2029881..2030102 + 222 WP_198807832.1 hypothetical protein -
GFS31_RS08995 2030154..2030378 + 225 WP_198807833.1 DUF433 domain-containing protein Antitoxin
GFS31_RS09000 2030375..2030716 + 342 WP_198807834.1 DUF5615 family PIN-like protein Toxin
GFS31_RS09005 2030907..2031230 + 324 WP_198807835.1 nucleotidyltransferase family protein -
GFS31_RS09010 2031335..2031892 - 558 WP_198807836.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
GFS31_RS09015 2031942..2033159 - 1218 WP_198807837.1 hybrid sensor histidine kinase/response regulator -
GFS31_RS09020 2033186..2033617 - 432 WP_198807838.1 response regulator -
GFS31_RS09025 2033720..2034838 - 1119 WP_198808125.1 DUF3326 domain-containing protein -
GFS31_RS09030 2034943..2035167 - 225 WP_198807839.1 hypothetical protein -
GFS31_RS09035 2035180..2035497 - 318 WP_198808126.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(4-79)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12341.07 Da        Isoelectric Point: 3.9941

>T143691 WP_198807834.1 NZ_CP046155:2030375-2030716 [Leptolyngbya sp. BL0902]
MTTLWIDAHLSPALATWITDNFDVTAVALRDIGLRDAEDPDIFEAAKSQSVIFMTKDRDFVDLVDRLGPPPQIIWLTCGN
TSNARLREILGSVLPTALEILCSGESLVEIGGD

Download         Length: 342 bp

>T143691 NZ_CP061329:1998869-1998972 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8234.66 Da        Isoelectric Point: 5.0187

>AT143691 WP_198807833.1 NZ_CP046155:2030154-2030378 [Leptolyngbya sp. BL0902]
MSKLLERITINPKQCGGRPCIRGMRIRVSDILDLFAAGLSAEEILEDLPDLEMEDIQASLTYAARKLNHPILVA

Download         Length: 225 bp

>AT143691 NZ_CP061329:c1999010-1998739 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References