143686

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3474272..3474622 Replicon chromosome
Accession NZ_CP046148
Organism Xanthomonas oryzae pv. oryzae strain ITCCBB0002

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag GKO49_RS16725 Protein ID WP_011257368.1
Coordinates 3474488..3474622 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag GKO49_RS16720 Protein ID WP_011407410.1
Coordinates 3474272..3474424 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKO49_RS16695 3470543..3471226 - 684 WP_011257363.1 dTMP kinase -
GKO49_RS16700 3471706..3472002 - 297 WP_012446308.1 hypothetical protein -
GKO49_RS16705 3472009..3472248 - 240 WP_011257365.1 hypothetical protein -
GKO49_RS16710 3472245..3472919 - 675 WP_011257366.1 hypothetical protein -
GKO49_RS16715 3473241..3474164 + 924 WP_011407409.1 arginase -
GKO49_RS16720 3474272..3474424 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
GKO49_RS16725 3474488..3474622 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
GKO49_RS16730 3474866..3475075 + 210 WP_011407411.1 CsbD family protein -
GKO49_RS16735 3475244..3476533 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
GKO49_RS16740 3476586..3477608 + 1023 WP_075239893.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T143686 WP_011257368.1 NZ_CP046148:3474488-3474622 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T143686 NZ_CP061329:871607-872014 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGTGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT143686 WP_011407410.1 NZ_CP046148:3474272-3474424 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT143686 NZ_CP061329:871360-871626 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References