Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 1397802..1399321 | Replicon | chromosome |
| Accession | NZ_CP046148 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain ITCCBB0002 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | A0A0K0GMB6 |
| Locus tag | GKO49_RS06540 | Protein ID | WP_011259680.1 |
| Coordinates | 1397802..1398725 (-) | Length | 308 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | A0A854CLN1 |
| Locus tag | GKO49_RS06545 | Protein ID | WP_011409027.1 |
| Coordinates | 1398722..1399321 (-) | Length | 200 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GKO49_RS06505 | 1393400..1393552 | + | 153 | Protein_1241 | SAM-dependent methyltransferase | - |
| GKO49_RS06510 | 1393664..1395040 | + | 1377 | WP_154741210.1 | IS5 family transposase | - |
| GKO49_RS06515 | 1395061..1395593 | + | 533 | Protein_1243 | methyltransferase domain-containing protein | - |
| GKO49_RS06520 | 1395610..1396119 | - | 510 | WP_011259678.1 | hypothetical protein | - |
| GKO49_RS06525 | 1396544..1396786 | - | 243 | WP_011259679.1 | hypothetical protein | - |
| GKO49_RS06530 | 1397252..1397440 | + | 189 | Protein_1246 | DNA-binding protein | - |
| GKO49_RS06535 | 1397474..1397722 | + | 249 | WP_033013473.1 | hypothetical protein | - |
| GKO49_RS06540 | 1397802..1398725 | - | 924 | WP_011259680.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| GKO49_RS06545 | 1398722..1399321 | - | 600 | WP_011409027.1 | AbiEi antitoxin N-terminal domain-containing protein | Antitoxin |
| GKO49_RS06555 | 1399656..1399976 | + | 321 | WP_011259682.1 | hypothetical protein | - |
| GKO49_RS06560 | 1400008..1400496 | + | 489 | WP_044756654.1 | BrxE family protein | - |
| GKO49_RS06565 | 1401010..1401011 | - | 2 | WP_094187731.1 | IS5 family transposase | - |
| GKO49_RS06570 | 1401410..1402730 | + | 1321 | Protein_1253 | IS701 family transposase | - |
| GKO49_RS06575 | 1402833..1403764 | + | 932 | Protein_1254 | IS30 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 1393664..1395040 | 1376 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 34114.16 Da Isoelectric Point: 5.4588
>T143684 WP_011259680.1 NZ_CP046148:c1398725-1397802 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
Download Length: 924 bp
>T143684 NZ_CP061329:279885-280160 [Escherichia coli]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATAGTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGCAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATAGTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGCAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA
Antitoxin
Download Length: 200 a.a. Molecular weight: 22037.74 Da Isoelectric Point: 10.1240
>AT143684 WP_011409027.1 NZ_CP046148:c1399321-1398722 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
Download Length: 600 bp
>AT143684 NZ_CP061329:280157-280516 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCAGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCAGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMB6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A854CLN1 |