Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1131413..1132910 Replicon chromosome
Accession NZ_CP046120
Organism Novosphingobium sp. Gsoil 351

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag GKE62_RS05410 Protein ID WP_154691345.1
Coordinates 1132026..1132910 (+) Length 295 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag GKE62_RS05405 Protein ID WP_154691344.1
Coordinates 1131413..1132033 (+) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKE62_RS05375 1126533..1127732 + 1200 WP_154691340.1 EamA family transporter RarD -
GKE62_RS05380 1127747..1127919 - 173 Protein_1054 transposase domain-containing protein -
GKE62_RS05385 1128102..1130318 - 2217 WP_154691341.1 TonB-dependent receptor -
GKE62_RS05390 1130488..1130949 - 462 WP_195908602.1 DUF3363 domain-containing protein -
GKE62_RS18405 1130836..1131081 + 246 WP_195908728.1 hypothetical protein -
GKE62_RS05395 1131066..1131224 + 159 WP_154691342.1 Lrp/AsnC ligand binding domain-containing protein -
GKE62_RS05400 1131190..1131327 + 138 WP_154691343.1 hypothetical protein -
GKE62_RS05405 1131413..1132033 + 621 WP_154691344.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
GKE62_RS05410 1132026..1132910 + 885 WP_154691345.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
GKE62_RS05415 1133267..1133842 + 576 WP_154691346.1 sigma-70 family RNA polymerase sigma factor -
GKE62_RS05420 1133839..1134765 + 927 WP_154691347.1 FecR domain-containing protein -
GKE62_RS05425 1134793..1136781 - 1989 WP_154691348.1 relaxase/mobilization nuclease and DUF3363 domain-containing protein -
GKE62_RS05430 1137111..1137461 - 351 WP_154691349.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 901298..1347496 446198


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-266)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(21-55)


Sequences

Toxin        


Download         Length: 295 a.a.        Molecular weight: 32550.42 Da        Isoelectric Point: 5.4858

>T143674 WP_154691345.1 NZ_CP046120:1132026-1132910 [Novosphingobium sp. Gsoil 351]
MARPPVNIAKSVKDRLLNIARQEGRAFDVLLVRFALERLLYRLSISPHREQFVLKGGMLVTAWIDDDNRVTRDADFLGFG
DADPHKLIADFRGIMVIEGGDGLVFDTGALTATAIRDEMEYGGVRIKTAAYLERTRISVIIDIGFGDAMAVTPQQLDFPT
LLDLPVPRIRAYPPSTVIAEKFQAMVALGVLNSRMKDYYDLWAIPRNVVIAPEDLDAAILATFTRRGTAIPTERPPGLST
ETTQDQAKRRQWSAYAKSLELEGVAFGTVADAVWAYVGPSCERLTVNPSVTRPE

Download         Length: 885 bp

>T143674 NZ_CP061316:c1305787-1305593 [Polynucleobacter sp. AP-Jannik-300A-C4]
ATGCACAGTAAAAAACTAATTGAGCTATTGACGAGTGACGGGTGGGTACTCAGTAGGATGAGGGGTTCGCATCATATCTT
CATTCACAGAACAAAGGATGGGCATATTTGCATTCCTCATCCTAAAAAGGATTTGGGTCTTGGTTTAGTGGAAAAAATAT
TAAAACAGGCAGATATCAAGAGGGGTAATAAATGA

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 22590.03 Da        Isoelectric Point: 10.0179

>AT143674 WP_154691344.1 NZ_CP046120:1131413-1132033 [Novosphingobium sp. Gsoil 351]
MASAEISQRTKLRDLFAAHTMMRAGELRTAGIGPQTIARAVEDGELERISRGLYQHRDTQIEEHQILAEAATRVPKGVIA
LTSALAFHGLTDQMPRRVWIAIGTSDWSPVPSYPPLRIVRLTAPYLREGIEHHVIAGVKVPVYSIPKTLADMFRNPKLVD
RSVAVEGLRSALEQRKATPSEIAEGAKAGGAWKTMHPFLEALTANG

Download         Length: 621 bp

>AT143674 NZ_CP061316:c1305596-1305204 [Polynucleobacter sp. AP-Jannik-300A-C4]
ATGAAATATCCGATTGCAATTGAGCCGGGATCTAGCAAGGAAGCCTGGGGTGTCGTTGTGCCAGATTTGGCAGGCTGTTT
CTCAGCTGGAGATAGAGATATTGATGAAGCTATAGAAAACGCAAAAGAGGCTATAGAGATTTGGATTGAGCTTGCTTTGG
GGCATAATCAAGAAATACCAAAACCAAGCTCACTGAGGGAATTGCAAAAGCGGAAAGAATTTAAAGGGTGGGTTTGGGCA
ATTGTAGAGATTGATCCAGCATTGCTTTCTGATGAAATAGAGCGAATAAATATCACCCTTCCAAAAAGGGTATTGGCTAG
ATTGGATGCAAAAGCAAAAAAAGCCGGAGAAAACAGATCCGCATTCATTGCACATTTGGCATTAACTGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References