Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 1121281..1122100 Replicon chromosome
Accession NZ_CP046115
Organism Klebsiella oxytoca strain P620

Toxin (Protein)


Gene name yjhX Uniprot ID -
Locus tag GJ746_RS05235 Protein ID WP_154679233.1
Coordinates 1121281..1121538 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag GJ746_RS05240 Protein ID WP_154679234.1
Coordinates 1121549..1122100 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJ746_RS05220 1117051..1117827 - 777 WP_154679230.1 Uxu operon transcriptional regulator -
GJ746_RS05225 1117964..1119439 - 1476 WP_154679231.1 fructuronate reductase -
GJ746_RS05230 1119513..1120697 - 1185 WP_154679232.1 mannonate dehydratase -
GJ746_RS05235 1121281..1121538 + 258 WP_154679233.1 YjhX family toxin Toxin
GJ746_RS05240 1121549..1122100 + 552 WP_154679234.1 N-acetyltransferase Antitoxin
GJ746_RS05245 1122118..1123746 + 1629 WP_154679235.1 SAM-dependent methyltransferase -
GJ746_RS05250 1123798..1124961 - 1164 WP_154679236.1 MFS transporter -
GJ746_RS05255 1124978..1126255 - 1278 WP_154679237.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(25-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T143639 WP_154679233.1 NZ_CP046115:1121281-1121538 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRITSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T143639 NZ_CP061298:284805-285203 [Polynucleobacter paludilacus]
ATGATCAAGTATTTGCTTGATACCAATATCGTGATTTATGTTCTCAAGCGCAGGCCCATTGAGGCCTTAGAAGCCTTTAA
TAAAAACGCCAATCGTATGGCAATTTCAAGTATCACTCTCTCAGAGCTCATCTATGGCGCTGAAAAGAGCGCAAATGTCG
ATAAAAATCTTGAGGCTGTTGAGGATTTTGTTAGTCACCTTGATGTTCTGTCCTATGACGCTAAAGCATCCCAGCAGTAT
GGGCAAATTAAAGCTGGTCTAGAAAAGCGCGGGGAACTTATCGGAGAGAATGACATCCATATTGCTGCCCATGCGATTAG
CCAGGGCCTAATTCTGGTCAGTAACAATTTAAAAGAGTTCAAAAGGGTGCCTAACCTTGCTTTAGAGAATTGGGTTTAA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20144.12 Da        Isoelectric Point: 6.3246

>AT143639 WP_154679234.1 NZ_CP046115:1121549-1122100 [Klebsiella oxytoca]
MTNHNFTFHITTECDAGDICEVETRAFGFSKEAELVADLLNDESACPMLSLLARHNGKAVGHILFSRATFKGESDSPLMH
ILAPLAVIPEYQGMGVGGWLIQNGIEHLKAMGSLAVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQPLSA
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT143639 NZ_CP061298:284572-284805 [Polynucleobacter paludilacus]
ATTACTACTTCCACAGTTTTTACGAACAATCGCTCTCAAGCCGTGCGTCTACCCACTGAGGCTCGTTTACCCGATGCGGT
GAAAAAGGTCATTGTGCGCACCCGTGGCCACGAGAGAATCATCACCCCTATTGAAAATACTTGGGACTATTTTTTTCTTA
GTGGCCCACTGGTGACTGACGACTTTATGAGCGAGCGTGGAGAGCAAAAACCTGCAGTTCGAGAGTCTTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References