Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 310724..311252 | Replicon | plasmid pTHAF191d_c |
Accession | NZ_CP046067 | ||
Organism | Vibrio sp. THAF191d |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | GGC04_RS26150 | Protein ID | WP_152472625.1 |
Coordinates | 310724..311014 (-) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A7Y3YX34 |
Locus tag | GGC04_RS26155 | Protein ID | WP_006958739.1 |
Coordinates | 311004..311252 (-) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GGC04_RS26115 | 306233..306976 | + | 744 | WP_152472629.1 | transporter substrate-binding domain-containing protein | - |
GGC04_RS26120 | 307427..307882 | - | 456 | WP_152472628.1 | DUF2079 domain-containing protein | - |
GGC04_RS26125 | 307879..309045 | - | 1167 | WP_152472906.1 | hypothetical protein | - |
GGC04_RS26130 | 309335..309448 | + | 114 | WP_152472627.1 | DUF3265 domain-containing protein | - |
GGC04_RS26135 | 309504..309803 | - | 300 | WP_043011872.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
GGC04_RS26140 | 309811..310053 | - | 243 | WP_152472626.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
GGC04_RS26145 | 310329..310565 | + | 237 | WP_021458677.1 | hypothetical protein | - |
GGC04_RS26150 | 310724..311014 | - | 291 | WP_152472625.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
GGC04_RS26155 | 311004..311252 | - | 249 | WP_006958739.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
GGC04_RS26160 | 311309..311437 | + | 129 | WP_144382900.1 | DUF3265 domain-containing protein | - |
GGC04_RS26165 | 311583..312173 | + | 591 | WP_040122585.1 | Crp/Fnr family transcriptional regulator | - |
GGC04_RS26170 | 312235..312681 | + | 447 | WP_152472624.1 | isoprenylcysteine carboxylmethyltransferase family protein | - |
GGC04_RS26175 | 312803..313030 | + | 228 | Protein_303 | isocitrate lyase/phosphoenolpyruvate mutase family protein | - |
GGC04_RS26180 | 313432..313911 | - | 480 | WP_152472623.1 | hypothetical protein | - |
GGC04_RS26185 | 314692..315027 | + | 336 | WP_064487238.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | htpB | 1..396761 | 396761 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11247.22 Da Isoelectric Point: 10.5339
>T143506 WP_152472625.1 NZ_CP046067:c311014-310724 [Vibrio sp. THAF191d]
MTYKLDFKKSALKEWKKLGATLQQQFKKKLIERLDNPHVLASKLSGADNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYRKAMNRLDD
MTYKLDFKKSALKEWKKLGATLQQQFKKKLIERLDNPHVLASKLSGADNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYRKAMNRLDD
Download Length: 291 bp
>T143506 NZ_CP061170:c904097-903837 [Microbacterium sp. HY82]
ATGAGCCGCGCGCTCGCGTTCGACAAGAACGGTTGGGAAGACTACGTCTATTGGCAAACCCAAGACCGCAAGACACTCAA
ACGGATCAACACGCTCATCGCAGACGTGCTCCGCGACCCATTCACCGGGATCGGAAAACCGGAACCACTCAAGCACATCC
TCAGCGGCGCCTGGTCGCGGCGCATCGACGAAACGAACCGACTCGTCTACTACGTCACCGACGACCACATTGTGATCCTC
CAAGCACGCGATCACTATTGA
ATGAGCCGCGCGCTCGCGTTCGACAAGAACGGTTGGGAAGACTACGTCTATTGGCAAACCCAAGACCGCAAGACACTCAA
ACGGATCAACACGCTCATCGCAGACGTGCTCCGCGACCCATTCACCGGGATCGGAAAACCGGAACCACTCAAGCACATCC
TCAGCGGCGCCTGGTCGCGGCGCATCGACGAAACGAACCGACTCGTCTACTACGTCACCGACGACCACATTGTGATCCTC
CAAGCACGCGATCACTATTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9030.29 Da Isoelectric Point: 3.9610
>AT143506 WP_006958739.1 NZ_CP046067:c311252-311004 [Vibrio sp. THAF191d]
MTTRILADVAASITELKANPMKVATSANGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL
MTTRILADVAASITELKANPMKVATSANGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL
Download Length: 249 bp
>AT143506 NZ_CP061170:c904345-904094 [Microbacterium sp. HY82]
ATGCCCGCAATCACAGCAACTGAAGCACGCAAGAGCCTGTTCGGACTCATCCAGCGCGTCAACGATGACCACACTGCGGT
CGAGGTTGTTTCCAAGCACGGCAACGCAGTTATCCTCTCGAAAGACGACTACGACGCAATCACCGAGACCGCTTACTTGC
TGCGCAACTCCGCAAACGCTGAGCGTCTACTCGACGCGATCGAGCGCGCTCGACGCGGCGAGTTTGAACAGCACGATCTT
CTCGAAGCATGA
ATGCCCGCAATCACAGCAACTGAAGCACGCAAGAGCCTGTTCGGACTCATCCAGCGCGTCAACGATGACCACACTGCGGT
CGAGGTTGTTTCCAAGCACGGCAACGCAGTTATCCTCTCGAAAGACGACTACGACGCAATCACCGAGACCGCTTACTTGC
TGCGCAACTCCGCAAACGCTGAGCGTCTACTCGACGCGATCGAGCGCGCTCGACGCGGCGAGTTTGAACAGCACGATCTT
CTCGAAGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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