143506

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 310724..311252 Replicon plasmid pTHAF191d_c
Accession NZ_CP046067
Organism Vibrio sp. THAF191d

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GGC04_RS26150 Protein ID WP_152472625.1
Coordinates 310724..311014 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7Y3YX34
Locus tag GGC04_RS26155 Protein ID WP_006958739.1
Coordinates 311004..311252 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GGC04_RS26115 306233..306976 + 744 WP_152472629.1 transporter substrate-binding domain-containing protein -
GGC04_RS26120 307427..307882 - 456 WP_152472628.1 DUF2079 domain-containing protein -
GGC04_RS26125 307879..309045 - 1167 WP_152472906.1 hypothetical protein -
GGC04_RS26130 309335..309448 + 114 WP_152472627.1 DUF3265 domain-containing protein -
GGC04_RS26135 309504..309803 - 300 WP_043011872.1 type II toxin-antitoxin system RelE/ParE family toxin -
GGC04_RS26140 309811..310053 - 243 WP_152472626.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GGC04_RS26145 310329..310565 + 237 WP_021458677.1 hypothetical protein -
GGC04_RS26150 310724..311014 - 291 WP_152472625.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GGC04_RS26155 311004..311252 - 249 WP_006958739.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GGC04_RS26160 311309..311437 + 129 WP_144382900.1 DUF3265 domain-containing protein -
GGC04_RS26165 311583..312173 + 591 WP_040122585.1 Crp/Fnr family transcriptional regulator -
GGC04_RS26170 312235..312681 + 447 WP_152472624.1 isoprenylcysteine carboxylmethyltransferase family protein -
GGC04_RS26175 312803..313030 + 228 Protein_303 isocitrate lyase/phosphoenolpyruvate mutase family protein -
GGC04_RS26180 313432..313911 - 480 WP_152472623.1 hypothetical protein -
GGC04_RS26185 314692..315027 + 336 WP_064487238.1 helix-turn-helix domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..396761 396761


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 11247.22 Da        Isoelectric Point: 10.5339

>T143506 WP_152472625.1 NZ_CP046067:c311014-310724 [Vibrio sp. THAF191d]
MTYKLDFKKSALKEWKKLGATLQQQFKKKLIERLDNPHVLASKLSGADNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYRKAMNRLDD

Download         Length: 291 bp

>T143506 NZ_CP061170:c904097-903837 [Microbacterium sp. HY82]
ATGAGCCGCGCGCTCGCGTTCGACAAGAACGGTTGGGAAGACTACGTCTATTGGCAAACCCAAGACCGCAAGACACTCAA
ACGGATCAACACGCTCATCGCAGACGTGCTCCGCGACCCATTCACCGGGATCGGAAAACCGGAACCACTCAAGCACATCC
TCAGCGGCGCCTGGTCGCGGCGCATCGACGAAACGAACCGACTCGTCTACTACGTCACCGACGACCACATTGTGATCCTC
CAAGCACGCGATCACTATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9030.29 Da        Isoelectric Point: 3.9610

>AT143506 WP_006958739.1 NZ_CP046067:c311252-311004 [Vibrio sp. THAF191d]
MTTRILADVAASITELKANPMKVATSANGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL

Download         Length: 249 bp

>AT143506 NZ_CP061170:c904345-904094 [Microbacterium sp. HY82]
ATGCCCGCAATCACAGCAACTGAAGCACGCAAGAGCCTGTTCGGACTCATCCAGCGCGTCAACGATGACCACACTGCGGT
CGAGGTTGTTTCCAAGCACGGCAACGCAGTTATCCTCTCGAAAGACGACTACGACGCAATCACCGAGACCGCTTACTTGC
TGCGCAACTCCGCAAACGCTGAGCGTCTACTCGACGCGATCGAGCGCGCTCGACGCGGCGAGTTTGAACAGCACGATCTT
CTCGAAGCATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A7Y3YX34

References