Detailed information of TA system TA143503

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 113639..114137
• Replicon: plasmid pTHAF191d_c
• Accession: NZ_CP046067
• Organism: Vibrio sp. THAF191d

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GGC04_RS25275
• Protein ID: WP_152472926.1
• Coordinates: 113958..114137 (+)
• Length: 60 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GGC04_RS25270
• Protein ID: WP_152472736.1
• Coordinates: 113639..113863 (+)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GGC04_RS25250	108650..109330	-	681	WP_152472927.1	hypothetical protein	-
GGC04_RS25255	109891..111543	+	1653	WP_152472742.1	hypothetical protein	-
GGC04_RS25260	111554..112261	+	708	WP_152472740.1	OmpA family protein	-
GGC04_RS25265	112306..113385	+	1080	WP_152472738.1	HNH endonuclease	-
GGC04_RS25270	113639..113863	+	225	WP_152472736.1	damage-inducible protein J	Antitoxin
GGC04_RS25275	113958..114137	+	180	WP_152472926.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GGC04_RS25280	114363..115331	-	969	WP_152472734.1	hypothetical protein	-
GGC04_RS25285	115463..115735	-	273	WP_152472733.1	hypothetical protein	-
GGC04_RS25290	115800..117893	-	2094	WP_152472732.1	TonB-dependent siderophore receptor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	htpB	1..396761	396761

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-55)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6766.98 Da
• Isoelectric Point: 9.2052

>T143503 WP_152472926.1 NZ_CP046067:113958-114137 [Vibrio sp. THAF191d]
IIEARVENLLEQPHMGVQRDGIRGRLLNTPKISMMVSYCESDTIHIMRVLHQKQKLPAA

Nucleotide

• Length: 180 bp

>T143503 NZ_CP061169:c95242-94838 [Microbacterium sp. HY60]
ATGCGTCCTGCTGCGAAAGGCCTTCTCGACACGAGCGTGTTCATAGCCCTTGAGTCAGGTCGACCAATGAATGCCGAGAT
GCTGCCAGACCAGAGTGTTATCTGTCCGGTGACGATCGCTGAGTTGCAGGCCGGTGTGCTGAGTATCGCCGACGTCGACG
TTCGCGCGCGACGGCTGTCCACGCTAGAGTCCACGATGGACATCGAATTGCTCGCGATTGATGCCGAAGTTGCAGCTCAT
TGGGCGCGCCTGAGAGTACATCTCGCCGAGAGCGGCCGCCGCGTCAACGTCAATGACCTCTGGATCGCGGCGACAGCGGC
CGCCAACGGGGTTCCCATCGTGACGCAAGACGACGACTTCGATCCACTTGAGGGCGCTCATGGCGTTACTGTGATTCGCG
TCTGA

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8613.85 Da
• Isoelectric Point: 9.2860

>AT143503 WP_152472736.1 NZ_CP046067:113639-113863 [Vibrio sp. THAF191d]
MDTRIPFGIDDETKRLAQQLADQKRKALFHDARLTEQVNLAFEKFDSKKVTFVDHESAKSCMAERKAKICNRDK

Nucleotide

• Length: 225 bp

>AT143503 NZ_CP061169:c95502-95242 [Microbacterium sp. HY60]
ATGGCTGAGATAGCAGCACGAGAACTCCGGAATAGCACCGCCGAAGTCCTGCGACGAGTAGAAGCAGGTGAGCCCGTGAC
AATCACCTCCCGCGGTCGTCCAGTCGCAGAGCTCACACCGGTGCGTTCGGCGCGTCGAAGGCCAATTTCACGCGCAGACC
TCACACGGCGCCTGAGCCGAACGCAGGCCGATTCTGGACTTCGCGAAGATTTGGCGTTGTTGGCTGGCGAGACCACTGAC
GACCTCGGCCCGATCCGCTGA