Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /HTH_XRE(antitoxin)
Location 1887119..1887925 Replicon chromosome
Accession NZ_CP046028
Organism Staphylococcus chromogenes strain 1401

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag GJU84_RS09255 Protein ID WP_165885855.1
Coordinates 1887461..1887925 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag GJU84_RS09250 Protein ID WP_107372887.1
Coordinates 1887119..1887448 (+) Length 110 a.a.

Genomic Context

GJU84_RS09235GJU84_RS09250GJU84_RS09255GJU84_RS09260GJU84_RS09265GJU84_RS09270GJU84_RS09200GJU84_RS09205GJU84_RS09210GJU84_RS09215GJU84_RS09220GJU84_RS09225GJU84_RS09230GJU84_RS09240GJU84_RS09245GJU84_RS09275GJU84_RS09280
Location: 1886261..1886500 (240 bp)
Type: Others
Protein ID: WP_057510934.1
Location: 1887119..1887448 (330 bp)
Type: Antitoxin
Protein ID: WP_107372887.1
Location: 1887461..1887925 (465 bp)
Type: Toxin
Protein ID: WP_165885855.1
Location: 1887941..1888477 (537 bp)
Type: Others
Protein ID: WP_165885856.1
Location: 1888596..1889111 (516 bp)
Type: Others
Protein ID: WP_165885857.1
Location: 1889173..1890222 (1050 bp)
Type: Others
Protein ID: WP_165885858.1
Location: 1882707..1883207 (501 bp)
Type: Others
Protein ID: WP_165885850.1
Location: 1883224..1884558 (1335 bp)
Type: Others
Protein ID: WP_165885851.1
Location: 1884542..1885252 (711 bp)
Type: Others
Protein ID: WP_165885852.1
Location: 1885252..1885470 (219 bp)
Type: Others
Protein ID: WP_165885853.1
Location: 1885467..1885733 (267 bp)
Type: Others
Protein ID: WP_157950523.1
Location: 1885815..1885991 (177 bp)
Type: Others
Protein ID: WP_165885854.1
Location: 1885981..1886160 (180 bp)
Type: Others
Protein ID: WP_107362511.1
Location: 1886490..1886669 (180 bp)
Type: Others
Protein ID: WP_057510935.1
Location: 1886682..1886927 (246 bp)
Type: Others
Protein ID: WP_107372884.1
Location: 1890290..1891687 (1398 bp)
Type: Others
Protein ID: WP_037572364.1
Location: 1891762..1892211 (450 bp)
Type: Others
Protein ID: WP_037572365.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GJU84_RS092001882707..1883207-501WP_165885850.1DUF669 domain-containing protein-
GJU84_RS092051883224..1884558-1335WP_165885851.1DEAD/DEAH box helicase-
GJU84_RS092101884542..1885252-711WP_165885852.1AAA family ATPase-
GJU84_RS092151885252..1885470-219WP_165885853.1DUF2483 family protein-
GJU84_RS092201885467..1885733-267WP_157950523.1DUF1108 family protein-
GJU84_RS092251885815..1885991-177WP_165885854.1hypothetical protein-
GJU84_RS092301885981..1886160-180WP_107362511.1hypothetical protein-
GJU84_RS092351886261..1886500+240WP_057510934.1hypothetical protein-
GJU84_RS092401886490..1886669-180WP_057510935.1hypothetical protein-
GJU84_RS092451886682..1886927-246WP_107372884.1helix-turn-helix domain-containing protein-
GJU84_RS092501887119..1887448+330WP_107372887.1helix-turn-helix domain-containing proteinAntitoxin
GJU84_RS092551887461..1887925+465WP_165885855.1ImmA/IrrE family metallo-endopeptidaseToxin
GJU84_RS092601887941..1888477+537WP_165885856.1Ltp family lipoprotein-
GJU84_RS092651888596..1889111+516WP_165885857.1hypothetical protein-
GJU84_RS092701889173..1890222+1050WP_165885858.1site-specific integrase-
GJU84_RS092751890290..1891687-1398WP_037572364.1Fe-S cluster assembly protein SufB-
GJU84_RS092801891762..1892211-450WP_037572365.1SUF system NifU family Fe-S cluster assembly protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--1842949..190874765798


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

IrrE N-terminal-like domain

(32-116)

Antitoxin

Cro/C1-type helix-turn-helix domain

(11-65)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 18282.81 Da        Isoelectric Point: 6.4964

>T143434 WP_165885855.1 NZ_CP046028:1887461-1887925 [Staphylococcus chromogenes]
MGLYEETLIQHDYIEVREANVLPDNLDGVWLGDLILIKRNLPEKKKVEVLFEELAHHKLTYGDITDQKKFNNRKFENYAR
RYSYETSMPLSGIVEAFKQGVHNLYELANFFEISEGHVLDCIEHYKKKHGLSTFNEGHLIQFEPLRVFKYKNYQ

Download         Length: 465 bp

>T143434 NZ_CP061088:c227976-227680 [Brucella sp. 6810]
ATGGCCCTTGAAACCACTCGTTTCGATATTCTCGACCATCTCAAGACGCCGGAGGAGCGCCTTGCTTATCTCGAAGCAGC
ATTTGAGGATGGCGACCCTTCTCTTATCGCTCATGCCCTCGGCGATGTGGCCCGCTCCGTTGGTATGACTGCCGTTGCCA
AAGAAGCAGGCATTACCCGTGAGGCGCTTTACAGATCTCTCAGCGAAAATGGCGACCCGAAACTATCGACCTTGCTTGGC
GTTACCAAAGCCCTCGGCATTCATTTGACCGTCGGGCCAGACAAACACGCCGCCTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12766.37 Da        Isoelectric Point: 7.3179

>AT143434 WP_107372887.1 NZ_CP046028:1887119-1887448 [Staphylococcus chromogenes]
MRNNDEIITIIKTSMKEQNLSLSELARRVGVAKSAVSRYLNLTREFPLNRAEDFAKALSISTEYLLGFEKSEQKHEQPQH
RAAHLEGELTDDEWQRVLDYADYIRSRRK

Download         Length: 330 bp

>AT143434 NZ_CP061088:c228268-227978 [Brucella sp. 6810]
ATGATCGAAGTTCGCCAAACCACAGCATTCACAAAATGGCTCAACGAGCTTCGAGACACCAATGCGCGTTTAAGGATTGC
CACTCGTATCCGACGAATGGAGCTTGGCAATCCAGGTGATGTGAAAGCCGTGGGTGAAGGTGTGAGCGAGATGCGTATTA
CCTATGGCCCCGGCTATCGGGTTTATTTCGTGACCATGGGTTCAACCATTGTCGTTCTGTTATGTGGCGGTGACAAGTCA
TCACAAAGCCGGGATATTGCCGTGGCGAAACAAATGGCGAAGGAGATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References