Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 919156..919937 Replicon chromosome
Accession NZ_CP046028
Organism Staphylococcus chromogenes strain 1401

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag GJU84_RS04435 Protein ID WP_157946077.1
Coordinates 919773..919937 (+) Length 55 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag GJU84_RS04430 Protein ID WP_105986518.1
Coordinates 919156..919755 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJU84_RS04410 915349..916071 + 723 WP_037577247.1 amino acid ABC transporter ATP-binding protein -
GJU84_RS04415 916359..917492 + 1134 WP_165885573.1 tRNA epoxyqueuosine(34) reductase QueG -
GJU84_RS04420 917489..917959 + 471 WP_165885574.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
GJU84_RS04425 917977..919137 + 1161 WP_165885575.1 N-acetylglucosamine-6-phosphate deacetylase -
GJU84_RS04430 919156..919755 + 600 WP_105986518.1 glucosamine-6-phosphate isomerase Antitoxin
GJU84_RS04435 919773..919937 + 165 WP_157946077.1 hypothetical protein Toxin
GJU84_RS04440 920037..920447 + 411 WP_103159619.1 hypothetical protein -
GJU84_RS04445 920592..921977 + 1386 WP_037577233.1 class II fumarate hydratase -
GJU84_RS04450 921999..923525 + 1527 WP_165885576.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(135-197)


Sequences

Toxin        


Download         Length: 55 a.a.        Molecular weight: 6336.67 Da        Isoelectric Point: 3.8825

>T143433 WP_157946077.1 NZ_CP046028:919773-919937 [Staphylococcus chromogenes]
MTEEKHIEHENEMVDDFDDLVSLGKEMEQISEANDEEKENQTHDASIRSDKTEE

Download         Length: 165 bp

>T143433 NZ_CP061088:136767-137171 [Brucella sp. 6810]
TTGAGCAAGCTTTACATGCTGGACACCAACATCGTGTCGGATCTTGCTCGTAACCCTCATGGCCCTGTAGCAAAACATAT
CGCTCGCGTGGGGGCTGATGCGATTTGCGTAAGCATCATTACCGCCTGCGAACTGCGTTACGGTTGTGCGAAAAAGGGTT
CGCCAAGACTGCTCGCACAGATAGAGGCAATACTGGATAGCATTGAAATTCTGCCGCTCGATGTTCCTGCCGATACGGAG
TATGGGGGCATACGGGCAGAACTGGAAGCTGATGGAAAGCCTATCGGTCCCAATGACTTTCTTATCGCGGCTCACGCTTG
CGCACTCGGTGCGGTTCTGGTTACGGCCAATGTCGGTGAGTTTACCCGCATCCGTAAACTTGCTGTTGAAAACTGGTTGA
ATTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22354.27 Da        Isoelectric Point: 5.8826

>AT143433 WP_105986518.1 NZ_CP046028:919156-919755 [Staphylococcus chromogenes]
MAMNFKVFKDKDTAAIYAADIIRKQFNNNPTTIAGFHLSGEEAPVLDYLKRNVDDHAVDFSQIHVLDYDKQTSYFKALGV
PEKQIHEIPEDDDVEKFIEHKAKTKDNKGKLTLQVVSINQNGEFGVPVNNGLKPAREIFVIVTGHDKADVIKKLYEDNGN
TSFIPSSLKTHRMVNVILDEAAAQGLPADVREYFTSLYA

Download         Length: 600 bp

>AT143433 NZ_CP061088:136501-136770 [Brucella sp. 6810]
ATGGCACACGCAAGACGTATCGAGCCAACGCCTGCGCGCGAGGCAAAGCTTTTTCGCAACAATAAGAGTCAGGCAGTTCG
TATTCCGGCTGATTTTGAGTTTCCGGGGAACCGTGTGCTTATCCATCGTGAAGGGGACAAGCTCATCATTGAACCTGTTC
GCCGAAAGAATCTGCTCGAAGTACTGGCAGGATTAAAGCCTCTTGGACCAGAGGACGCTTTCCCGGACATTGATGATACA
GCCCTCCCGCTTAAGGATGTAGACCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References