Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 919156..919937 Replicon chromosome
Accession NZ_CP046028
Organism Staphylococcus chromogenes strain 1401

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag GJU84_RS04435 Protein ID WP_157946077.1
Coordinates 919773..919937 (+) Length 55 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag GJU84_RS04430 Protein ID WP_105986518.1
Coordinates 919156..919755 (+) Length 200 a.a.

Genomic Context

GJU84_RS04410GJU84_RS04415GJU84_RS04420GJU84_RS04425GJU84_RS04430GJU84_RS04435GJU84_RS04440GJU84_RS04445GJU84_RS04450
Location: 915349..916071 (723 bp)
Type: Others
Protein ID: WP_037577247.1
Location: 916359..917492 (1134 bp)
Type: Others
Protein ID: WP_165885573.1
Location: 917489..917959 (471 bp)
Type: Others
Protein ID: WP_165885574.1
Location: 917977..919137 (1161 bp)
Type: Others
Protein ID: WP_165885575.1
Location: 919156..919755 (600 bp)
Type: Antitoxin
Protein ID: WP_105986518.1
Location: 919773..919937 (165 bp)
Type: Toxin
Protein ID: WP_157946077.1
Location: 920037..920447 (411 bp)
Type: Others
Protein ID: WP_103159619.1
Location: 920592..921977 (1386 bp)
Type: Others
Protein ID: WP_037577233.1
Location: 921999..923525 (1527 bp)
Type: Others
Protein ID: WP_165885576.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GJU84_RS04410915349..916071+723WP_037577247.1amino acid ABC transporter ATP-binding protein-
GJU84_RS04415916359..917492+1134WP_165885573.1tRNA epoxyqueuosine(34) reductase QueG-
GJU84_RS04420917489..917959+471WP_165885574.1tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL-
GJU84_RS04425917977..919137+1161WP_165885575.1N-acetylglucosamine-6-phosphate deacetylase-
GJU84_RS04430919156..919755+600WP_105986518.1glucosamine-6-phosphate isomeraseAntitoxin
GJU84_RS04435919773..919937+165WP_157946077.1hypothetical proteinToxin
GJU84_RS04440920037..920447+411WP_103159619.1hypothetical protein-
GJU84_RS04445920592..921977+1386WP_037577233.1class II fumarate hydratase-
GJU84_RS04450921999..923525+1527WP_165885576.1exopolyphosphatase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(135-197)


Sequences

Toxin        


Download         Length: 55 a.a.        Molecular weight: 6336.67 Da        Isoelectric Point: 3.8825

>T143433 WP_157946077.1 NZ_CP046028:919773-919937 [Staphylococcus chromogenes]
MTEEKHIEHENEMVDDFDDLVSLGKEMEQISEANDEEKENQTHDASIRSDKTEE

Download         Length: 165 bp

>T143433 NZ_CP061088:136767-137171 [Brucella sp. 6810]
TTGAGCAAGCTTTACATGCTGGACACCAACATCGTGTCGGATCTTGCTCGTAACCCTCATGGCCCTGTAGCAAAACATAT
CGCTCGCGTGGGGGCTGATGCGATTTGCGTAAGCATCATTACCGCCTGCGAACTGCGTTACGGTTGTGCGAAAAAGGGTT
CGCCAAGACTGCTCGCACAGATAGAGGCAATACTGGATAGCATTGAAATTCTGCCGCTCGATGTTCCTGCCGATACGGAG
TATGGGGGCATACGGGCAGAACTGGAAGCTGATGGAAAGCCTATCGGTCCCAATGACTTTCTTATCGCGGCTCACGCTTG
CGCACTCGGTGCGGTTCTGGTTACGGCCAATGTCGGTGAGTTTACCCGCATCCGTAAACTTGCTGTTGAAAACTGGTTGA
ATTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22354.27 Da        Isoelectric Point: 5.8826

>AT143433 WP_105986518.1 NZ_CP046028:919156-919755 [Staphylococcus chromogenes]
MAMNFKVFKDKDTAAIYAADIIRKQFNNNPTTIAGFHLSGEEAPVLDYLKRNVDDHAVDFSQIHVLDYDKQTSYFKALGV
PEKQIHEIPEDDDVEKFIEHKAKTKDNKGKLTLQVVSINQNGEFGVPVNNGLKPAREIFVIVTGHDKADVIKKLYEDNGN
TSFIPSSLKTHRMVNVILDEAAAQGLPADVREYFTSLYA

Download         Length: 600 bp

>AT143433 NZ_CP061088:136501-136770 [Brucella sp. 6810]
ATGGCACACGCAAGACGTATCGAGCCAACGCCTGCGCGCGAGGCAAAGCTTTTTCGCAACAATAAGAGTCAGGCAGTTCG
TATTCCGGCTGATTTTGAGTTTCCGGGGAACCGTGTGCTTATCCATCGTGAAGGGGACAAGCTCATCATTGAACCTGTTC
GCCGAAAGAATCTGCTCGAAGTACTGGCAGGATTAAAGCCTCTTGGACCAGAGGACGCTTTCCCGGACATTGATGATACA
GCCCTCCCGCTTAAGGATGTAGACCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References