Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE(toxin) |
Location | 682261..682768 | Replicon | chromosome |
Accession | NZ_CP046027 | ||
Organism | Neisseria brasiliensis strain N.177.16 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | GJV52_RS03460 | Protein ID | WP_100562529.1 |
Coordinates | 682499..682768 (+) | Length | 90 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | GJV52_RS03455 | Protein ID | WP_095501920.1 |
Coordinates | 682261..682509 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GJV52_RS03430 | 678094..678738 | + | 645 | WP_095501915.1 | DUF452 family protein | - |
GJV52_RS03435 | 678735..679493 | + | 759 | WP_095501916.1 | malonyl-ACP O-methyltransferase BioC | - |
GJV52_RS03440 | 679559..680200 | + | 642 | WP_195690078.1 | dethiobiotin synthase | - |
GJV52_RS03445 | 680265..681239 | + | 975 | WP_100562525.1 | iron chelate uptake ABC transporter family permease subunit | - |
GJV52_RS03450 | 681300..682058 | + | 759 | WP_100562527.1 | ATP-binding cassette domain-containing protein | - |
GJV52_RS03455 | 682261..682509 | + | 249 | WP_095501920.1 | plasmid stabilization protein | Antitoxin |
GJV52_RS03460 | 682499..682768 | + | 270 | WP_100562529.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
GJV52_RS03465 | 682810..683274 | - | 465 | WP_095502188.1 | YchJ family protein | - |
GJV52_RS03470 | 683401..684288 | + | 888 | WP_100562531.1 | RnfABCDGE type electron transport complex subunit B | - |
GJV52_RS03475 | 684352..684681 | + | 330 | WP_095502186.1 | hypothetical protein | - |
GJV52_RS03480 | 685048..686079 | + | 1032 | WP_095502185.1 | type I glyceraldehyde-3-phosphate dehydrogenase | - |
GJV52_RS03485 | 686139..686327 | - | 189 | WP_157798096.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
GJV52_RS03490 | 686402..686590 | - | 189 | WP_095502183.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 10679.60 Da Isoelectric Point: 10.2908
>T143428 WP_100562529.1 NZ_CP046027:682499-682768 [Neisseria brasiliensis]
MTYKLKFKASAKREFDKLDRTVKEQFKKKLKKILENPTIPKNKLHGSDYRNMYKIELRAVGYRLVYEVIDDELVIIVIEV
GRRDTIYLN
MTYKLKFKASAKREFDKLDRTVKEQFKKKLKKILENPTIPKNKLHGSDYRNMYKIELRAVGYRLVYEVIDDELVIIVIEV
GRRDTIYLN
Download Length: 270 bp
>T143428 NZ_CP061084:c350011-349541 [Pantoea sp. MT58]
ATGGAAGATGGCACGGTTATGAATGGATGGCACGTTTATGTTCATCCCTGTTTTGAATCACAGCTGATTGCGCTGACCAA
TGAAGTGGAGTCACTCAGGGCTAAATATCCTGAAAGTTACCAGCGAATAGCGACGACTAAGCTTTTAGCCGCGGTGTTTA
AAGTTATCAATAGTGAGATTTGCGCCGATTCACATCATGCAAAGTTTCGCCAGGGCGATACGCTGGGAGAACAAAATAAG
CATTGGTTCCGTGCGAAGTTTTTAATGCAGTATCGTTTGTTCTTTAGATTCAGCGAACAACATAAAACCATTATCCTTGC
ATGGATGAATGACGCCGAGACCAAACGTGCCTATGGCAGTAAACGTGACGCTTATAAAGTATTTTCAGGAATGTTGCATA
ACGGCTACCCACCAGACGACTGGGCATTGCTGTTAAAGCAATCTCAGGATTGGGATAATACAAACTCGTAA
ATGGAAGATGGCACGGTTATGAATGGATGGCACGTTTATGTTCATCCCTGTTTTGAATCACAGCTGATTGCGCTGACCAA
TGAAGTGGAGTCACTCAGGGCTAAATATCCTGAAAGTTACCAGCGAATAGCGACGACTAAGCTTTTAGCCGCGGTGTTTA
AAGTTATCAATAGTGAGATTTGCGCCGATTCACATCATGCAAAGTTTCGCCAGGGCGATACGCTGGGAGAACAAAATAAG
CATTGGTTCCGTGCGAAGTTTTTAATGCAGTATCGTTTGTTCTTTAGATTCAGCGAACAACATAAAACCATTATCCTTGC
ATGGATGAATGACGCCGAGACCAAACGTGCCTATGGCAGTAAACGTGACGCTTATAAAGTATTTTCAGGAATGTTGCATA
ACGGCTACCCACCAGACGACTGGGCATTGCTGTTAAAGCAATCTCAGGATTGGGATAATACAAACTCGTAA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9334.63 Da Isoelectric Point: 4.1958
>AT143428 WP_095501920.1 NZ_CP046027:682261-682509 [Neisseria brasiliensis]
MTKPIHSRFVASISDLKKNPMETVKSGQGDVVAILNRNTPAFYCIPADLYDEIFEILEDQYLMRVAMERDNEPSIEVSVD
DL
MTKPIHSRFVASISDLKKNPMETVKSGQGDVVAILNRNTPAFYCIPADLYDEIFEILEDQYLMRVAMERDNEPSIEVSVD
DL
Download Length: 249 bp
>AT143428 NZ_CP061084:c350362-350018 [Pantoea sp. MT58]
ATGGGAACGCTGACCCATACCAACATCTCTCTGCGCGCTACATCAAAACTGACAGCCCGCAGCCAGACCACGATCCCTGC
CGCAGTTCGTGATGCGATGAATCTGCAACCTGGTGAGAATATCGAATACGCTGTTCTGCCTGGCGGCAAAGTCCTTATTA
CCCGTCAGGAAACGGTGACTGATGATGATCCGGTGATGGCGAGCTTTCTGAGTTTTCTTGCTGCTGATATGTGCAACACG
CCTTCAAATATCAAAACGCTTGATCGAGGATTATTAACTCGCATTACTTCGTTGACCGAAGGTATGGACGTTGATTTGGA
TGCTCCACTCATGGACGATGAGTAA
ATGGGAACGCTGACCCATACCAACATCTCTCTGCGCGCTACATCAAAACTGACAGCCCGCAGCCAGACCACGATCCCTGC
CGCAGTTCGTGATGCGATGAATCTGCAACCTGGTGAGAATATCGAATACGCTGTTCTGCCTGGCGGCAAAGTCCTTATTA
CCCGTCAGGAAACGGTGACTGATGATGATCCGGTGATGGCGAGCTTTCTGAGTTTTCTTGCTGCTGATATGTGCAACACG
CCTTCAAATATCAAAACGCTTGATCGAGGATTATTAACTCGCATTACTTCGTTGACCGAAGGTATGGACGTTGATTTGGA
TGCTCCACTCATGGACGATGAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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