Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 682261..682768 Replicon chromosome
Accession NZ_CP046027
Organism Neisseria brasiliensis strain N.177.16

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GJV52_RS03460 Protein ID WP_100562529.1
Coordinates 682499..682768 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GJV52_RS03455 Protein ID WP_095501920.1
Coordinates 682261..682509 (+) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJV52_RS03430 678094..678738 + 645 WP_095501915.1 DUF452 family protein -
GJV52_RS03435 678735..679493 + 759 WP_095501916.1 malonyl-ACP O-methyltransferase BioC -
GJV52_RS03440 679559..680200 + 642 WP_195690078.1 dethiobiotin synthase -
GJV52_RS03445 680265..681239 + 975 WP_100562525.1 iron chelate uptake ABC transporter family permease subunit -
GJV52_RS03450 681300..682058 + 759 WP_100562527.1 ATP-binding cassette domain-containing protein -
GJV52_RS03455 682261..682509 + 249 WP_095501920.1 plasmid stabilization protein Antitoxin
GJV52_RS03460 682499..682768 + 270 WP_100562529.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GJV52_RS03465 682810..683274 - 465 WP_095502188.1 YchJ family protein -
GJV52_RS03470 683401..684288 + 888 WP_100562531.1 RnfABCDGE type electron transport complex subunit B -
GJV52_RS03475 684352..684681 + 330 WP_095502186.1 hypothetical protein -
GJV52_RS03480 685048..686079 + 1032 WP_095502185.1 type I glyceraldehyde-3-phosphate dehydrogenase -
GJV52_RS03485 686139..686327 - 189 WP_157798096.1 type II toxin-antitoxin system RelE/ParE family toxin -
GJV52_RS03490 686402..686590 - 189 WP_095502183.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-87)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10679.60 Da        Isoelectric Point: 10.2908

>T143428 WP_100562529.1 NZ_CP046027:682499-682768 [Neisseria brasiliensis]
MTYKLKFKASAKREFDKLDRTVKEQFKKKLKKILENPTIPKNKLHGSDYRNMYKIELRAVGYRLVYEVIDDELVIIVIEV
GRRDTIYLN

Download         Length: 270 bp

>T143428 NZ_CP061084:c350011-349541 [Pantoea sp. MT58]
ATGGAAGATGGCACGGTTATGAATGGATGGCACGTTTATGTTCATCCCTGTTTTGAATCACAGCTGATTGCGCTGACCAA
TGAAGTGGAGTCACTCAGGGCTAAATATCCTGAAAGTTACCAGCGAATAGCGACGACTAAGCTTTTAGCCGCGGTGTTTA
AAGTTATCAATAGTGAGATTTGCGCCGATTCACATCATGCAAAGTTTCGCCAGGGCGATACGCTGGGAGAACAAAATAAG
CATTGGTTCCGTGCGAAGTTTTTAATGCAGTATCGTTTGTTCTTTAGATTCAGCGAACAACATAAAACCATTATCCTTGC
ATGGATGAATGACGCCGAGACCAAACGTGCCTATGGCAGTAAACGTGACGCTTATAAAGTATTTTCAGGAATGTTGCATA
ACGGCTACCCACCAGACGACTGGGCATTGCTGTTAAAGCAATCTCAGGATTGGGATAATACAAACTCGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9334.63 Da        Isoelectric Point: 4.1958

>AT143428 WP_095501920.1 NZ_CP046027:682261-682509 [Neisseria brasiliensis]
MTKPIHSRFVASISDLKKNPMETVKSGQGDVVAILNRNTPAFYCIPADLYDEIFEILEDQYLMRVAMERDNEPSIEVSVD
DL

Download         Length: 249 bp

>AT143428 NZ_CP061084:c350362-350018 [Pantoea sp. MT58]
ATGGGAACGCTGACCCATACCAACATCTCTCTGCGCGCTACATCAAAACTGACAGCCCGCAGCCAGACCACGATCCCTGC
CGCAGTTCGTGATGCGATGAATCTGCAACCTGGTGAGAATATCGAATACGCTGTTCTGCCTGGCGGCAAAGTCCTTATTA
CCCGTCAGGAAACGGTGACTGATGATGATCCGGTGATGGCGAGCTTTCTGAGTTTTCTTGCTGCTGATATGTGCAACACG
CCTTCAAATATCAAAACGCTTGATCGAGGATTATTAACTCGCATTACTTCGTTGACCGAAGGTATGGACGTTGATTTGGA
TGCTCCACTCATGGACGATGAGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References