Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 296205..296740 Replicon plasmid pAUSMDU00010532_01
Accession NZ_CP045959
Organism Salmonella enterica subsp. enterica serovar Birkenhead strain AUSMDU00010532

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GJE06_RS23995 Protein ID WP_154074340.1
Coordinates 296205..296492 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GJE06_RS24000 Protein ID WP_154074341.1
Coordinates 296489..296740 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJE06_RS23975 291770..291970 - 201 Protein_279 transposase -
GJE06_RS23980 292302..292928 - 627 Protein_280 IS6 family transposase -
GJE06_RS23985 292915..293445 + 531 Protein_281 DDE-type integrase/transposase/recombinase -
GJE06_RS23990 295589..296119 - 531 Protein_282 IS3 family transposase -
GJE06_RS23995 296205..296492 - 288 WP_154074340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GJE06_RS24000 296489..296740 - 252 WP_154074341.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GJE06_RS24005 297168..297560 - 393 WP_154074342.1 helix-turn-helix transcriptional regulator -
GJE06_RS24015 298261..299277 + 1017 WP_154074343.1 IS110 family transposase -
GJE06_RS24020 299503..299619 - 117 Protein_287 transposase -
GJE06_RS24025 299668..299949 + 282 WP_154074344.1 hypothetical protein -
GJE06_RS24030 300169..300567 - 399 WP_154074345.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..329074 329074


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)

Antitoxin

Toxin YoeB

(5-84)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 14146.97 Da        Isoelectric Point: 5.5500

>T143101 WP_154074340.1 NZ_CP045959:c296492-296205 [Salmonella enterica subsp. enterica serovar Birkenhead]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFF

Download         Length: 288 bp

>T143101 NZ_CP060946:c1140456-1140205 [Escherichia coli O157:H7 str. EC10]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 12380.85 Da        Isoelectric Point: 5.5500

>AT143101 WP_154074341.1 NZ_CP045959:c296740-296489 [Salmonella enterica subsp. enterica serovar Birkenhead]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Download         Length: 252 bp

>AT143101 NZ_CP060946:c1140208-1139954 [Escherichia coli O157:H7 str. EC10]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References