Detailed information of TA system TA143100

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 261417..261970
• Replicon: plasmid pAUSMDU00010532_01
• Accession: NZ_CP045959
• Organism: Salmonella enterica subsp. enterica serovar Birkenhead strain AUSMDU00010532

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: GJE06_RS23850
• Protein ID: WP_154074328.1
• Coordinates: 261417..261731 (-)
• Length: 105 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: -
• Locus tag: GJE06_RS23855
• Protein ID: WP_080071031.1
• Coordinates: 261734..261970 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GJE06_RS23825	256904..257290	-	387	WP_154074325.1	relaxosome protein TraM	-
GJE06_RS23830	257714..258223	+	510	WP_154074371.1	transglycosylase SLT domain-containing protein	-
GJE06_RS23835	258529..259274	-	746	Protein_251	DUF932 domain-containing protein	-
GJE06_RS23845	260868..261029	-	162	WP_195183093.1	LysR family transcriptional regulator	-
GJE06_RS23850	261417..261731	-	315	WP_154074328.1	CcdB family protein	Toxin
GJE06_RS23855	261734..261970	-	237	WP_080071031.1	type II toxin-antitoxin system CcdA family antitoxin	Antitoxin
GJE06_RS23860	262825..263505	-	681	WP_154074329.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..329074	329074

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 105 a.a.
• Molecular weight: 15471.56 Da
• Isoelectric Point: 5.5500

>T143100 WP_154074328.1 NZ_CP045959:c261731-261417 [Salmonella enterica subsp. enterica serovar Birkenhead]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 315 bp

>T143100 NZ_CP060946:c1140208-1139954 [Escherichia coli O157:H7 str. EC10]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 11644.97 Da
• Isoelectric Point: 5.5500

>AT143100 WP_080071031.1 NZ_CP045959:c261970-261734 [Salmonella enterica subsp. enterica serovar Birkenhead]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 237 bp

>AT143100 NZ_CP060946:c1140456-1140205 [Escherichia coli O157:H7 str. EC10]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA