Detailed information of TA system TA143099

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 229188..229813
• Replicon: plasmid pAUSMDU00010532_01
• Accession: NZ_CP045959
• Organism: Salmonella enterica subsp. enterica serovar Birkenhead strain AUSMDU00010532

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: GJE06_RS23660
• Protein ID: WP_154074294.1
• Coordinates: 229415..229813 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: GJE06_RS23655
• Protein ID: WP_195183092.1
• Coordinates: 229188..229415 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GJE06_RS23655	229188..229415	+	228	WP_195183092.1	antitoxin	Antitoxin
GJE06_RS23660	229415..229813	+	399	WP_154074294.1	tRNA(fMet)-specific endonuclease VapC	Toxin
GJE06_RS23665	229822..231978	-	2157	WP_154074295.1	type IV conjugative transfer system coupling protein TraD	-
GJE06_RS23670	232355..233086	-	732	WP_154074296.1	complement resistance protein TraT	-
GJE06_RS23675	233122..233616	-	495	WP_154074297.1	entry exclusion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..329074	329074

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 17065.17 Da
• Isoelectric Point: 12.9205

>T143099 WP_154074294.1 NZ_CP045959:229415-229813 [Salmonella enterica subsp. enterica serovar Birkenhead]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 399 bp

>T143099 NZ_CP060946:c952005-951902 [Escherichia coli O157:H7 str. EC10]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 9759.25 Da
• Isoelectric Point: 12.6750

>AT143099 WP_195183092.1 NZ_CP045959:229188-229415 [Salmonella enterica subsp. enterica serovar Birkenhead]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 228 bp

>AT143099 NZ_CP060946:951864-952135 [Escherichia coli O157:H7 str. EC10]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT