Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2152..2711 Replicon plasmid pAUSMDU00010529_02
Accession NZ_CP045951
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain AUSMDU00010529

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GJE11_RS24130 Protein ID WP_000421275.1
Coordinates 2436..2711 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A418GAX7
Locus tag GJE11_RS24125 Protein ID WP_024186313.1
Coordinates 2152..2436 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJE11_RS24120 46..1077 + 1032 WP_000907872.1 hypothetical protein -
GJE11_RS24125 2152..2436 + 285 WP_024186313.1 ribbon-helix-helix protein, CopG family Antitoxin
GJE11_RS24130 2436..2711 + 276 WP_000421275.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GJE11_RS24135 2817..3098 + 282 WP_001105066.1 hypothetical protein -
GJE11_RS24690 3289..3555 - 267 WP_000627833.1 hypothetical protein -
GJE11_RS24140 3624..4049 - 426 WP_001389390.1 hypothetical protein -
GJE11_RS24145 4105..4707 - 603 WP_000517691.1 hypothetical protein -
GJE11_RS24150 5061..6407 + 1347 WP_001132018.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..93769 93769


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11810.03 Da        Isoelectric Point: 12.7590

>T143095 WP_000421275.1 NZ_CP045951:2436-2711 [Salmonella enterica subsp. enterica serovar Typhimurium]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKK

Download         Length: 276 bp

>T143095 NZ_CP060946:c321574-321467 [Escherichia coli O157:H7 str. EC10]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 12194.55 Da        Isoelectric Point: 12.7731

>AT143095 WP_024186313.1 NZ_CP045951:2152-2436 [Salmonella enterica subsp. enterica serovar Typhimurium]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKK

Download         Length: 285 bp

>AT143095 NZ_CP060946:321624-321687 [Escherichia coli O157:H7 str. EC10]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A418GAX7

References