Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2085871..2086105 | Replicon | chromosome |
| Accession | NZ_CP045941 | ||
| Organism | Shigella flexneri 2a strain AUSMDU00010535 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2086001..2086104 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2085871..2086105 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GJE14_RS10370 | 2082426..2083088 | - | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
| GJE14_RS10375 | 2083112..2083768 | - | 657 | Protein_2019 | carbon-nitrogen hydrolase family protein | - |
| GJE14_RS10380 | 2083870..2084100 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| GJE14_RS10385 | 2084239..2084613 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| GJE14_RS10390 | 2084617..2085489 | + | 873 | Protein_2022 | copper homeostasis membrane protein CopD | - |
| GJE14_RS10395 | 2085502..2085843 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2085871..2086105 | - | 235 | - | - | Antitoxin |
| - | 2086001..2086104 | + | 104 | - | - | Toxin |
| GJE14_RS26165 | 2086236..2087313 | - | 1078 | Protein_2024 | phage integrase Arm DNA-binding domain-containing protein | - |
| GJE14_RS10410 | 2087279..2087560 | - | 282 | WP_005127484.1 | excisionase | - |
| GJE14_RS10415 | 2087677..2088525 | - | 849 | Protein_2026 | IS3-like element IS600 family transposase | - |
| GJE14_RS10420 | 2088580..2089775 | + | 1196 | Protein_2027 | IS3 family transposase | - |
| GJE14_RS10425 | 2089818..2090128 | - | 311 | Protein_2028 | transposase | - |
| GJE14_RS10430 | 2090192..2090659 | + | 468 | Protein_2029 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T143069 NZ_CP045941:2086001-2086104 [Shigella flexneri 2a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT143069 NZ_CP045941:c2086105-2085871 [Shigella flexneri 2a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
