Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/-
Location 2481258..2481670 Replicon chromosome
Accession NZ_CP045920
Organism Pseudactinotalea sp. HY158

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag GCE65_RS10925 Protein ID WP_153878410.1
Coordinates 2481258..2481410 (-) Length 51 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag GCE65_RS10930 Protein ID WP_153878411.1
Coordinates 2481440..2481670 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GCE65_RS10905 2477156..2478022 + 867 WP_153878407.1 sugar ABC transporter permease -
GCE65_RS10910 2478030..2478830 + 801 WP_153878408.1 carbohydrate ABC transporter permease -
GCE65_RS10915 2478838..2479644 + 807 WP_153879242.1 polyphenol oxidase family protein -
GCE65_RS10920 2479823..2480392 - 570 WP_153878409.1 hypothetical protein -
GCE65_RS10925 2481258..2481410 - 153 WP_153878410.1 hypothetical protein Toxin
GCE65_RS10930 2481440..2481670 - 231 WP_153878411.1 ribbon-helix-helix domain-containing protein Antitoxin
GCE65_RS10935 2481724..2482434 - 711 WP_153878412.1 sulfite exporter TauE/SafE family protein -
GCE65_RS10940 2482599..2484512 - 1914 WP_153878413.1 hypothetical protein -
GCE65_RS10945 2484512..2485213 - 702 WP_153878414.1 ATP-binding cassette domain-containing protein -
GCE65_RS10950 2485210..2485749 - 540 WP_153878415.1 PadR family transcriptional regulator -
GCE65_RS10955 2485845..2486075 + 231 WP_153878416.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Ribbon-helix-helix protein, CopG

(3-35)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5397.13 Da        Isoelectric Point: 10.8836

>T143000 WP_153878410.1 NZ_CP045920:c2481410-2481258 [Pseudactinotalea sp. HY158]
VSNDRTNVTVTRVGRGATMVVPLTSYVSRMFPFQAARPAVETGIDRDSVA

Download         Length: 153 bp

>T143000 NZ_CP060924:c630473-630009 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTTTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8148.03 Da        Isoelectric Point: 4.2676

>AT143000 WP_153878411.1 NZ_CP045920:c2481670-2481440 [Pseudactinotalea sp. HY158]
MKITIRLSDEDLAVLDDVVRRAGLPSRSAAVRRAIGLLRHPDLEGDYAAAWEEWSSSGEATAWAATSEDGLADAPP

Download         Length: 231 bp

>AT143000 NZ_CP060924:c630808-630473 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References