Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2416122..2416657 Replicon chromosome
Accession NZ_CP045913
Organism Serratia proteamaculans strain 336X

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GHV41_RS11740 Protein ID WP_099062250.1
Coordinates 2416382..2416657 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GHV41_RS11735 Protein ID WP_153858631.1
Coordinates 2416122..2416382 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GHV41_RS11715 2411454..2412101 + 648 WP_153858627.1 DcrB-related protein -
GHV41_RS11720 2412136..2412741 + 606 WP_153858628.1 glutathione S-transferase -
GHV41_RS11725 2412809..2414200 + 1392 WP_153858629.1 L-seryl-tRNA(Sec) selenium transferase -
GHV41_RS11730 2414197..2416038 + 1842 WP_153858630.1 selenocysteine-specific translation elongation factor -
GHV41_RS11735 2416122..2416382 + 261 WP_153858631.1 ribbon-helix-helix domain-containing protein Antitoxin
GHV41_RS11740 2416382..2416657 + 276 WP_099062250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GHV41_RS11745 2416732..2417979 - 1248 WP_153858632.1 MFS transporter -
GHV41_RS11750 2418398..2419390 + 993 WP_153858633.1 acyltransferase -
GHV41_RS11755 2419385..2420308 - 924 WP_153858634.1 DJ-1/PfpI family protein -
GHV41_RS11760 2420311..2420862 - 552 WP_153858635.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10804.61 Da        Isoelectric Point: 10.0859

>T142974 WP_099062250.1 NZ_CP045913:2416382-2416657 [Serratia proteamaculans]
MELKWTSKALSDLARLFEFLALANRTAAAHMMQALVAAPKVLRDNPRIGERLDEFLPQEVRRILIGHYEMRYQLHSSTIY
ILRIWHTREER

Download         Length: 276 bp

>T142974 NZ_CP060916:c64305-63925 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAACCGCTACGGCGGCCTGCCGGGAATGTC
AGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGCTATTTTTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACCGTAGGGGCTGCGACCGG
AGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTTCCGCGGAGTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9783.26 Da        Isoelectric Point: 4.8782

>AT142974 WP_153858631.1 NZ_CP045913:2416122-2416382 [Serratia proteamaculans]
MNTKVITAHVPLPLADKVDEMAAKLERSRGWIVKQALAAWLDQEEERRRLTLEALADVEQKNIIDHEMVEAWAASLDSEK
PLPVPR

Download         Length: 261 bp

>AT142974 NZ_CP060916:c64526-64305 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGCGGCAACCTTTCTGAAGTGCTCAACAATGTTGAAGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGTGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTCGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References