Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1239368..1239924 Replicon chromosome
Accession NZ_CP045913
Organism Serratia proteamaculans strain 336X

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GHV41_RS06090 Protein ID WP_153857944.1
Coordinates 1239634..1239924 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GHV41_RS06085 Protein ID WP_153857943.1
Coordinates 1239368..1239646 (+) Length 93 a.a.

Genomic Context

GHV41_RS06065GHV41_RS06070GHV41_RS06075GHV41_RS06080GHV41_RS06085GHV41_RS06090GHV41_RS06105GHV41_RS06110GHV41_RS06060GHV41_RS06095GHV41_RS06100
Location: 1235693..1237279 (1587 bp)
Type: Others
Protein ID: WP_153857939.1
Location: 1237305..1237496 (192 bp)
Type: Others
Protein ID: WP_153857940.1
Location: 1237493..1238893 (1401 bp)
Type: Others
Protein ID: WP_153857941.1
Location: 1238896..1239282 (387 bp)
Type: Others
Protein ID: WP_153857942.1
Location: 1239368..1239646 (279 bp)
Type: Antitoxin
Protein ID: WP_153857943.1
Location: 1239634..1239924 (291 bp)
Type: Toxin
Protein ID: WP_153857944.1
Location: 1242185..1243930 (1746 bp)
Type: Others
Protein ID: WP_153857947.1
Location: 1243927..1244877 (951 bp)
Type: Others
Protein ID: WP_153857948.1
Location: 1234708..1235547 (840 bp)
Type: Others
Protein ID: WP_153857938.1
Location: 1239934..1240818 (885 bp)
Type: Others
Protein ID: WP_153857945.1
Location: 1240824..1242047 (1224 bp)
Type: Others
Protein ID: WP_153857946.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GHV41_RS060601234708..1235547-840WP_153857938.1MurR/RpiR family transcriptional regulator-
GHV41_RS060651235693..1237279+1587WP_153857939.1gamma-glutamyltransferase family protein-
GHV41_RS060701237305..1237496+192WP_153857940.1oxalurate catabolism protein HpxX-
GHV41_RS060751237493..1238893+1401WP_153857941.1AtzE family amidohydrolase-
GHV41_RS060801238896..1239282+387WP_153857942.1oxalurate catabolism protein HpxZ-
GHV41_RS060851239368..1239646+279WP_153857943.1ribbon-helix-helix protein, CopG familyAntitoxin
GHV41_RS060901239634..1239924+291WP_153857944.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GHV41_RS060951239934..1240818-885WP_153857945.1siderophore-interacting protein-
GHV41_RS061001240824..1242047-1224WP_153857946.1MFS transporter-
GHV41_RS061051242185..1243930+1746WP_153857947.1IucA/IucC family siderophore biosynthesis protein-
GHV41_RS061101243927..1244877+951WP_153857948.1acetyltransferase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11027.57 Da        Isoelectric Point: 7.2006

>T142970 WP_153857944.1 NZ_CP045913:1239634-1239924 [Serratia proteamaculans]
VPQLIWTPAALQDIQRLYRFLAEKDLNSAKRAVVTIRRSINILAHQPQVGRPIEEMDTEFREWPIDFGNSGYIALYRFDG
NTAVLLAVRHQSEAGY

Download         Length: 291 bp

>T142970 NZ_CP060914:c4422621-4422334 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGCAAACAAGGCCAAAAGTAATCGGGTAAAACATGGCATCCGCTTTGAAGATGCGGT
GTTAGTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10806.98 Da        Isoelectric Point: 5.2246

>AT142970 WP_153857943.1 NZ_CP045913:1239368-1239646 [Serratia proteamaculans]
MTSATSIKIDEQLKQRVQQIAATRQRSAHWIMREAIREYVEREEKREALRKDALQAWEAYQANGKHLSQEEANNWLADLE
KGDDTEIPECHN

Download         Length: 279 bp

>AT142970 NZ_CP060914:c4422347-4422045 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCAATGTGCAGCATGAGGCCGAACTGAAGGCGCTGGCGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCAGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References