Detailed information of TA system TA142957

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 923782..925466
• Replicon: chromosome
• Accession: NZ_CP045912
• Organism: Xanthomonas oryzae pv. oryzicola strain 0-9

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: GHV42_RS04230
• Protein ID: WP_149621356.1
• Coordinates: 924852..925466 (-)
• Length: 205 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: GHV42_RS04225
• Protein ID: WP_149621355.1
• Coordinates: 923782..924855 (-)
• Length: 358 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GHV42_RS04205	919657..919983	-	327	WP_024710580.1	hypothetical protein	-
GHV42_RS04210	920287..921567	-	1281	WP_024710581.1	amidohydrolase family protein	-
GHV42_RS04215	921564..922973	-	1410	WP_024710582.1	amidohydrolase	-
GHV42_RS04220	923113..923673	+	561	WP_044750878.1	DUF924 family protein	-
GHV42_RS04225	923782..924855	-	1074	WP_149621355.1	macro domain-containing protein	Antitoxin
GHV42_RS04230	924852..925466	-	615	WP_149621356.1	DUF4433 domain-containing protein	Toxin
GHV42_RS04235	925836..926762	-	927	WP_024710586.1	Grx4 family monothiol glutaredoxin	-
GHV42_RS04240	926808..927599	+	792	WP_024710587.1	polysaccharide deacetylase family protein	-
GHV42_RS04250	927903..928574	-	672	WP_024745633.1	class I SAM-dependent methyltransferase	-
GHV42_RS04255	928897..929547	-	651	WP_024710589.1	SGNH/GDSL hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-203)

Antitoxin

• Macro domain (18-129)

Sequences

Toxin

Protein

• Length: 205 a.a.
• Molecular weight: 23757.97 Da
• Isoelectric Point: 7.9242

>T142957 WP_149621356.1 NZ_CP045912:c925466-924852 [Xanthomonas oryzae pv. oryzicola]
MIWRITHRGNLPWILDNGLHCGNAAVQSSSWVSIGNPELIDKRSSHPVPRPPGGFSNDYVPFYFTPFLPMLRNIHTAWGG
IQRRPNEDIVILVSSLHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIH
RHVPLDGLRGIVCHTDGLQQTIERQLQERNLKLPVHTRTGWYFR

Nucleotide

• Length: 615 bp

>T142957 NZ_CP060914:1327159-1327494 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin

Protein

• Length: 358 a.a.
• Molecular weight: 40084.13 Da
• Isoelectric Point: 6.0089

>AT142957 WP_149621355.1 NZ_CP045912:c924855-923782 [Xanthomonas oryzae pv. oryzicola]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDRADVRPLIEEVLAGLDTDILVFEPTLKYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECGLLEIQKLAWFLERNIERAGLPELDLRFSAHKYGPYADRLRHLLNGLDGSYLHCD
KRISDADPLDVIWFDDNRKSFVQTYLLKSEAKQYIPALEATAALIDGFESPFGMELLATVDWLIVQEGISAQVADVREGI
RHWPGDQEAAARKDRLFDDRALGIALKRLASGAIAVA

Nucleotide

• Length: 1074 bp

>AT142957 NZ_CP060914:1326911-1327159 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA