Detailed information of TA system TA142956

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 636575..638154
• Replicon: chromosome
• Accession: NZ_CP045912
• Organism: Xanthomonas oryzae pv. oryzicola strain 0-9

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: GHV42_RS02895
• Protein ID: WP_153816726.1
• Coordinates: 636575..637840 (+)
• Length: 422 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: A0A0C5UZA4
• Locus tag: GHV42_RS02900
• Protein ID: WP_044749828.1
• Coordinates: 637858..638154 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GHV42_RS02875	631786..632436	+	651	Protein_545	IS30 family transposase	-
GHV42_RS02880	632525..632803	-	279	WP_153817187.1	type I toxin-antitoxin system SymE family toxin	-
GHV42_RS02885	633580..635661	+	2082	Protein_547	hemagglutinin repeat-containing protein	-
GHV42_RS02890	635715..636200	+	486	Protein_548	IS30-like element IS1112a family transposase	-
GHV42_RS02895	636575..637840	+	1266	WP_153816726.1	avirulence protein	Toxin
GHV42_RS02900	637858..638154	+	297	WP_044749828.1	hypothetical protein	Antitoxin
GHV42_RS02905	638376..638642	+	267	Protein_551	transposase	-
GHV42_RS02910	638709..639134	-	426	Protein_552	DDE-type integrase/transposase/recombinase	-
GHV42_RS02915	639203..640305	+	1103	WP_153816727.1	IS3 family transposase	-
GHV42_RS02920	640335..640412	+	78	Protein_554	anti-sigma factor antagonist	-
GHV42_RS02925	640507..640682	+	176	Protein_555	HAD family hydrolase	-
GHV42_RS02930	640898..641650	-	753	WP_024712407.1	YceI family protein	-
GHV42_RS02935	641861..642451	-	591	WP_014504809.1	malonic semialdehyde reductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	619714..640305	20591

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (149-291)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 422 a.a.
• Molecular weight: 45187.78 Da
• Isoelectric Point: 6.9140

>T142956 WP_153816726.1 NZ_CP045912:636575-637840 [Xanthomonas oryzae pv. oryzicola]
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAVTHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI

Nucleotide

• Length: 1266 bp

>T142956 NZ_CP060914:1190823-1191230 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGTGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11327.83 Da
• Isoelectric Point: 5.2138

>AT142956 WP_044749828.1 NZ_CP045912:637858-638154 [Xanthomonas oryzae pv. oryzicola]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS

Nucleotide

• Length: 297 bp

>AT142956 NZ_CP060914:1190576-1190842 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0C5UZA4