Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/doc(antitoxin)
Location 2133938..2134341 Replicon chromosome
Accession NZ_CP045875
Organism Heliorestis convoluta strain HH

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag FTV88_RS10280 Protein ID WP_153725542.1
Coordinates 2133938..2134099 (-) Length 54 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag FTV88_RS10285 Protein ID WP_153725543.1
Coordinates 2134099..2134341 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FTV88_RS10260 2130080..2130466 - 387 WP_153725539.1 GyrI-like domain-containing protein -
FTV88_RS10265 2130678..2131688 + 1011 WP_153725540.1 arsenic resistance protein -
FTV88_RS10270 2132013..2132210 + 198 WP_153725541.1 hypothetical protein -
FTV88_RS10275 2132532..2133764 + 1233 WP_153726616.1 transposase -
FTV88_RS10280 2133938..2134099 - 162 WP_153725542.1 hypothetical protein Toxin
FTV88_RS10285 2134099..2134341 - 243 WP_153725543.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FTV88_RS10290 2134650..2135249 + 600 WP_153725544.1 helix-turn-helix domain-containing protein -
FTV88_RS10295 2135394..2135792 + 399 WP_153725545.1 IS200/IS605 family transposase -
FTV88_RS10300 2135789..2136895 + 1107 WP_207707854.1 transposase -
FTV88_RS10305 2137045..2138757 - 1713 WP_153725547.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

SpoVT-AbrB domain

(7-47)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 6187.13 Da        Isoelectric Point: 9.7814

>T142953 WP_153725542.1 NZ_CP045875:c2134099-2133938 [Heliorestis convoluta]
MRYLTEREVISINLLVIERYSPKEQKGVKIPELLNSAINRPKQSESTHVHNNL

Download         Length: 162 bp

>T142953 NZ_CP060914:c833808-833344 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTTTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9137.52 Da        Isoelectric Point: 5.1486

>AT142953 WP_153725543.1 NZ_CP045875:c2134341-2134099 [Heliorestis convoluta]
MERKLTKIGNSLGVTFPIELLNRLGLQQGDNVSVEEQGDTIVIRKSEKVQLPKGISSDFFDLLDKNMKEYDETLKKLVER

Download         Length: 243 bp

>AT142953 NZ_CP060914:c834143-833808 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References