Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 58621..59137 Replicon chromosome
Accession NZ_CP045871
Organism Litoricola lipolytica strain IMCC 1097

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag GH975_RS00285 Protein ID WP_153712579.1
Coordinates 58868..59137 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GH975_RS00280 Protein ID WP_153712578.1
Coordinates 58621..58875 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GH975_RS00255 54448..56298 + 1851 WP_153714744.1 polysaccharide biosynthesis protein -
GH975_RS00260 56328..56879 - 552 WP_153712575.1 sugar transferase -
GH975_RS00265 57109..57909 - 801 WP_211365853.1 IS3 family transposase -
GH975_RS00270 57930..58238 - 309 WP_153712577.1 transposase -
GH975_RS00275 58297..58473 - 177 Protein_54 transposase family protein -
GH975_RS00280 58621..58875 + 255 WP_153712578.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GH975_RS00285 58868..59137 + 270 WP_153712579.1 Txe/YoeB family addiction module toxin Toxin
GH975_RS11985 59294..59494 + 201 WP_170272491.1 integrase core domain-containing protein -
GH975_RS00295 59569..60522 - 954 WP_153712581.1 SDR family oxidoreductase -
GH975_RS00300 60522..61703 - 1182 WP_153712582.1 glycosyltransferase family 4 protein -
GH975_RS00305 61700..62014 - 315 WP_170272492.1 heparinase II/III family protein -
GH975_RS11990 61986..62369 - 384 WP_170272493.1 hypothetical protein -
GH975_RS00310 62516..63130 - 615 Protein_62 Gfo/Idh/MocA family oxidoreductase -
GH975_RS00315 63132..63449 - 318 WP_211365819.1 UDP-N-acetylglucosamine 2-epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 57930..58238 308


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10649.05 Da        Isoelectric Point: 8.8658

>T142951 WP_153712579.1 NZ_CP045871:58868-59137 [Litoricola lipolytica]
VISRQRLLSWTDDAWDDYLYWQTQDRKTLKRINKLVNDVKRSPFEGLGKPEPLKENLAGFWSRRIDDTNRLVYAVDDTAL
TIISCRYHY

Download         Length: 270 bp

>T142951 NZ_CP060914:c37377-37066 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9470.63 Da        Isoelectric Point: 6.4628

>AT142951 WP_153712578.1 NZ_CP045871:58621-58875 [Litoricola lipolytica]
MRIVSFTEARNSLKAVLDGVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPKNAEHLNRSIAQYRSGKTTERQ
LVGD

Download         Length: 255 bp

>AT142951 NZ_CP060914:c37065-36775 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References