Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4518502..4518640 Replicon chromosome
Accession NZ_CP045870
Organism Klebsiella aerogenes strain Y1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4518537..4518640 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4518502..4518640 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GIY00_RS21555 4513611..4515671 + 2061 WP_032708611.1 oligopeptidase B -
GIY00_RS21560 4515674..4516333 - 660 WP_015366006.1 exodeoxyribonuclease X -
GIY00_RS21565 4516413..4516643 - 231 WP_015366007.1 DNA polymerase III subunit theta -
GIY00_RS21570 4516778..4517152 + 375 WP_015366008.1 CopC domain-containing protein YobA -
GIY00_RS21575 4517156..4518025 + 870 WP_032708610.1 copper homeostasis membrane protein CopD -
GIY00_RS21580 4518039..4518380 + 342 WP_015705946.1 YebY family protein -
- 4518502..4518640 - 139 - - Antitoxin
- 4518537..4518640 + 104 - - Toxin
GIY00_RS21585 4518772..4519851 - 1080 WP_032708609.1 phage integrase Arm DNA-binding domain-containing protein -
GIY00_RS21590 4519826..4520098 - 273 WP_071609883.1 excisionase -
GIY00_RS21595 4520165..4520557 - 393 WP_155953466.1 hypothetical protein -
GIY00_RS21600 4520587..4521051 - 465 WP_196776118.1 siphovirus Gp157 family protein -
GIY00_RS21605 4521087..4523423 - 2337 WP_032708604.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4513611..4536811 23200


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T142943 NZ_CP045870:4518537-4518640 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 139 bp

>AT142943 NZ_CP045870:c4518640-4518502 [Klebsiella aerogenes]
AAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References