Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4487663..4487801 Replicon chromosome
Accession NZ_CP045869
Organism Klebsiella aerogenes strain Y3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4487698..4487801 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4487663..4487801 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GIY01_RS21405 4482772..4484832 + 2061 WP_032708611.1 oligopeptidase B -
GIY01_RS21410 4484835..4485494 - 660 WP_015366006.1 exodeoxyribonuclease X -
GIY01_RS21415 4485574..4485804 - 231 WP_015366007.1 DNA polymerase III subunit theta -
GIY01_RS21420 4485939..4486313 + 375 WP_015366008.1 CopC domain-containing protein YobA -
GIY01_RS21425 4486317..4487186 + 870 WP_032708610.1 copper homeostasis membrane protein CopD -
GIY01_RS21430 4487200..4487541 + 342 WP_015705946.1 YebY family protein -
- 4487663..4487801 - 139 - - Antitoxin
- 4487698..4487801 + 104 - - Toxin
GIY01_RS21435 4487933..4489012 - 1080 WP_032708609.1 phage integrase Arm DNA-binding domain-containing protein -
GIY01_RS21440 4488987..4489259 - 273 WP_071609883.1 excisionase -
GIY01_RS21445 4489326..4489718 - 393 WP_155953466.1 hypothetical protein -
GIY01_RS21450 4489748..4490212 - 465 WP_196776118.1 siphovirus Gp157 family protein -
GIY01_RS21455 4490248..4492584 - 2337 WP_032708604.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4481514..4516200 34686


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T142930 NZ_CP045869:4487698-4487801 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 139 bp

>AT142930 NZ_CP045869:c4487801-4487663 [Klebsiella aerogenes]
AAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References